Art

J-GLOBAL ID：201402261345948970   Reference number：14A0912174

A SIMPLE METHOD FOR THE PREPARATION OF PYRIMID[4,5-d]PYRIMIDINE-2,4(1H,3H)-DITHIONE DERIVATIVES

ピリミド[4,5-d]ピリミジン-2,4(1H,3H)-ジチオン誘導体の合成のための簡便法

Author (7)： KOBAYASHI Kazuhiro (Tottori Univ., Tottori, JPN) ,  KURODA Minami (Tottori Univ., Tottori, JPN) ,  TANAKA Noriyuki (Tottori Univ., Tottori, JPN) ,  YOKOI Yuki (Tottori Univ., Tottori, JPN) ,  KOBAYASHI Akihiro (Tottori Univ., Tottori, JPN) ,  HIYOSHI Hidetaka (Ihara Chemical Ind. Co., Ltd., Tokyo) ,  UMEZU Kazuto (Ihara Chemical Ind. Co., Ltd., Tokyo)
Material： Heterocycles  (International Journal for Reviews and Communications in Heterocyclic Chemistry)
Volume： 89  Issue： 8  Page： 1933-1939  Publication year： Aug. 01, 2014 
JST Material Number： S0966A  ISSN： 0385-5414  CODEN： HTCYAM  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *nitrogen heterocyclic compound ,  process(production) ,  method ,  isothiocyanate ,  *carboxamide ,  chemical synthesis ,  molecular structure ,  sodium compound ,  hydride
Semi thesaurus term： isothiocyanates ,  Pyrimidines ,  shortcut method ,  sodium hydride ,  two-stage process

JST classification (2)： Nitrogen heterocycles in general  (CF07040G) ,  Nitrogen derivatives of aromatic monocyclic carboxylic acids  (CF05200S)

Substance index (8)： 1-Phenyl-3-ethyl-4-thioxo-5-methoxy-7-methylthio-3,4-dihydropyrimido[4,5-d]pyrimidine-2(1H)-one ,  1-(2-Methylphenyl)-3-ethyl-4-thioxo-5-methoxy-7-methylthio-3,4-dihydropyrimido[4,5-d]pyrimidine-2(1H)-one ,  1-(3-Chlorophenyl)-3-ethyl-4-thioxo-5-methoxy-7-methylthio-3,4-dihydropyrimido[4,5-d]pyrimidine-2(1H)-one ,  1-(3-Methoxyphenyl)-3-ethyl-4-thioxo-5-methoxy-7-methylthio-3,4-dihydropyrimido[4,5-d]pyrimidine-2(1H)-one ,  1,3-Diethyl-4-thioxo-5-methoxy-7-methylthio-3,4-dihydropyrimido[4,5-d]pyrimidine-2(1H)-one ,  1-Phenyl-3-butyl-4-thioxo-5-methoxy-7-methylthio-3,4-dihydropyrimido[4,5-d]pyrimidine-2(1H)-one ,  1-(3,5-Dimethylphenyl)-3-butyl-4-thioxo-5-methoxy-7-methylthio-3,4-dihydropyrimido[4,5-d]pyrimidine-2(1H)-one ,  1-Cyclohexyl-3-butyl-4-thioxo-5-methoxy-7-methylthio-3,4-dihydropyrimido[4,5-d]pyrimidine-2(1H)-one

Reference (4)：

• A. Nagarajan, B. R. Meltsner, and T. J. Delia, J. Heterocycl. Chem., 1997, 34, 1581.
• R. Evers and E. Fischer, Z. Chem., 1980, 20, 412.
• K. Kobayashi, T. Suzuki, N. Matsumoto, H. Hiyoshi, and K. Umezu, Heterocycles, 2012, 85,1405.
• (a) K. Kobayashi, T. Suzuki, A. Imaoka, H. Hiyoshi, and K. Umezu, Heterocycles, 2013, 87, 885; (b) K. Kobayashi, K. Nakazawa, S. Yuba, H. Hiyoshi, and K. Umezu, Heterocycles, 2014, 90, in press; DOI: 10.3987/COM-14-S(K)5.

Terms in the title (4)： ピリミジン ,  ジチオン ,  誘導体 ,  簡便法