Art

J-GLOBAL ID：201402261887604924   Reference number：14A0774717

Development of Assay for Determining Free IgE Levels in Serum from Patients Treated with Omalizumab

オマリズマブで治療した患者の血清中の遊離IgE濃度を測定するためのアッセイの開発

Author (10)： ITO Reiko (Div. of Respiratory Medicine, Dep. of Internal Medicine, Nihon Univ. School of Medicine) ,  GON Yasuhiro (Div. of Respiratory Medicine, Dep. of Internal Medicine, Nihon Univ. School of Medicine) ,  NUNOMURA Satoshi (Allergy and Immunology Group, Res. Inst. of Medical Sci., Medical Education Plan and Promotion Room, Nihon Univ. ...) ,  ATSUTA Ryo (Dep. of Respiratory Medicine, Juntendo Univ. School of Medicine) ,  HARADA Norihiro (Dep. of Respiratory Medicine, Juntendo Univ. School of Medicine) ,  HATTORI Tomohiro (Div. of Respiratory Medicine, Dep. of Internal Medicine, Nihon Univ. School of Medicine) ,  MARUOKA Shuichiro (Div. of Respiratory Medicine, Dep. of Internal Medicine, Nihon Univ. School of Medicine) ,  OKAYAMA Yoshimichi (Allergy and Immunology Group, Res. Inst. of Medical Sci., Medical Education Plan and Promotion Room, Nihon Univ. ...) ,  RA Chisei (Allergy and Immunology Group, Res. Inst. of Medical Sci., Medical Education Plan and Promotion Room, Nihon Univ. ...) ,  HASHIMOTO Shu (Div. of Respiratory Medicine, Dep. of Internal Medicine, Nihon Univ. School of Medicine)
Material： Allergology International  (Allergol Int)
Volume： 63  Issue： Supplement.1  Page： S37-S47 (J-STAGE)  Publication year： 2014 
JST Material Number： L6446A  ISSN： 1323-8930  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： monoclonal antibody ,...
Semi thesaurus term： FcεRIα ,...

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JST classification (3)： Bioassay  (EA03060N) ,  Clinical application of drugs acting on respiration and respiratory system  (GW08020U) ,  Treatment for immunologic diseases,allergic diseases.  (GD04030Y)

Reference (30)：

• 1. Bousquet J, Lockey R, Malling HJ. Allergen immunotherapy: therapeutic vaccines for allergic diseases. A WHO position paper. J Allergy Clin Immunol 1998; 102(Pt 1): 558-62.
• 2. Milgrom H, Fick RB Jr, Su JQ et al. Treatment of allergic asthma with monoclonal anti-IgE antibody. rhuMAb-E25 Study Group. N Engl J Med 1999; 341: 1966-73.
• 3. Pelaia G, Gallelli L, Renda T et al. Update on optimal use of omalizumab in management of asthma. J Asthma Allergy 2011; 4: 49-59.
• 4. Chang TW, Shiung YY. Anti-IgE as a mast cell-stabilizing therapeutic agent. J Allergy Clin Immunol 2006; 117: 1203-12; quiz 13.
• 5. Beck LA, Marcotte GV, MacGlashan D, Togias A, Saini S. Omalizumab-induced reductions in mast cell Fce psilon RI expression and function. J Allergy Clin Immunol 2004; 114: 527-30.

Terms in the title (7)： オマリズマブ ,  治療 ,  患者 ,  血清 ,  IgE ,  アッセイ ,  開発