Art

J-GLOBAL ID：201402265283194880   Reference number：14A0165765

Miglitol prevents diet-induced obesity by stimulating brown adipose tissue and energy expenditure independent of preventing the digestion of carbohydrates

食餌誘発性肥満に対するミグリトールの予防効果は,褐色細胞を刺激しエネルギーを消費させることによっており,炭水化物の消化阻害とは独立した作用である

Author (16)： SASAKI Tsutomu (Lab. of Metabolic Signal, Metabolic Signal Res. Center, Inst. for Molecular and Cellular Regulation, Gunma Univ. ...) ,  SHIMPUKU Mayumi (Lab. of Metabolic Signal, Metabolic Signal Res. Center, Inst. for Molecular and Cellular Regulation, Gunma Univ. ...) ,  KITAZUMI Tomoya (Lab. of Metabolic Signal, Metabolic Signal Res. Center, Inst. for Molecular and Cellular Regulation, Gunma Univ. ...) ,  HIRAGA Haruna (Lab. of Metabolic Signal, Metabolic Signal Res. Center, Inst. for Molecular and Cellular Regulation, Gunma Univ. ...) ,  NAKAGAWA Yuko (Dep. of Cell Biology, Inst. for Molecular and Cellular Regulation, Gunma Univ., Maebashi, JPN) ,  SHIBATA Hiroshi (Dep. of Cell Biology, Inst. for Molecular and Cellular Regulation, Gunma Univ., Maebashi, JPN) ,  OKAMATSU-OGURA Yuko (Lab. of Biochemistry, Dep. of Biomedical Sciences, Graduate School of Veterinary Medicine, Hokkaido Univ., Sapporo, JPN) ,  KIKUCHI Osamu (Lab. of Metabolic Signal, Metabolic Signal Res. Center, Inst. for Molecular and Cellular Regulation, Gunma Univ. ...) ,  KIM Hye-jin (Lab. of Metabolic Signal, Metabolic Signal Res. Center, Inst. for Molecular and Cellular Regulation, Gunma Univ. ...) ,  FUJITA Yuki (Lab. of Metabolic Signal, Metabolic Signal Res. Center, Inst. for Molecular and Cellular Regulation, Gunma Univ. ...) ,  MARUYAMA Jun (Lab. of Metabolic Signal, Metabolic Signal Res. Center, Inst. for Molecular and Cellular Regulation, Gunma Univ. ...) ,  SUSANTI Vina Yanti (Lab. of Metabolic Signal, Metabolic Signal Res. Center, Inst. for Molecular and Cellular Regulation, Gunma Univ. ...) ,  YOKOTA-HASHIMOTO Hiromi (Lab. of Metabolic Signal, Metabolic Signal Res. Center, Inst. for Molecular and Cellular Regulation, Gunma Univ. ...) ,  KOBAYASHI Masaki (Lab. of Metabolic Signal, Metabolic Signal Res. Center, Inst. for Molecular and Cellular Regulation, Gunma Univ. ...) ,  SAITO Masayuki (Dep. of Nutrition, School of Nursing and Nutrition, Tenshi Coll., Sapporo, JPN) ,  KITAMURA Tadahiro (Lab. of Metabolic Signal, Metabolic Signal Res. Center, Inst. for Molecular and Cellular Regulation, Gunma Univ. ...)
Material： Endocrine Journal  (Endocr J)
Volume： 60  Issue： 10  Page： 1117-1129 (J-STAGE)  Publication year： 2013 
JST Material Number： F0625A  ISSN： 0918-8959  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Mus musculus ,...
Semi thesaurus term： brown cell

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=14A0165765&from=J-GLOBAL&jstjournalNo=F0625A") }}

JST classification (1)： Basic research of drugs acting on carbohydrate metabolism  (GW13020Q)

Substance index (1)： Miglitol

Reference (42)：

• 1. Ginter E, Simko V (2012) Type 2 diabetes mellitus, pandemic in 21st century. Adv Exp Med Biol 771: 42-50.
• 2. Ginter E, Simko V (2012) Global prevalence and future of diabetes mellitus. Adv Exp Med Biol 771: 35-41.
• 3. Eckel RH, Kahn SE, Ferrannini E, Goldfine AB, Nathan DM, et al. (2011) Obesity and type 2 diabetes: what can be unified and what needs to be individualized? Diabetes Care 34: 1424-1430.
• 4. Meneghini LF, Orozco-Beltran D, Khunti K, Caputo S, Damci T, et al. (2011) Weight beneficial treatments for type 2 diabetes. J Clin Endocrinol Metab 96: 3337-3353.
• 5. Ledford H (2010) Slim spoils for obesity drugs. Nature 468: 878.

Terms in the title (11)： 食餌 ,  肥満 ,  ミグリトール ,  予防効果 ,  褐色細胞 ,  刺激 ,  エネルギー ,  消費 ,  炭水化物 ,  消化 ,  阻害