Art

J-GLOBAL ID：201402281610929088   Reference number：14A0774758

X-Ray Crystallographic Structure of RNase Po1 That Exhibits Anti-tumor Activity

抗腫瘍活性を示すRNasePo1のX線結晶構造

Author (10)： KOBAYASHI Hiroko (School of Pharmacy, Nihon Univ.) ,  KATSUTANI Takuya (Inst. for Protein Res., Osaka Univ.) ,  HARA Yumiko (Inst. for Protein Res., Osaka Univ.) ,  MOTOYOSHI Naomi (School of Pharmacy, Nihon Univ.) ,  ITAGAKI Tadashi (School of Pharmacy, Nihon Univ.) ,  AKITA Fusamichi (Inst. for Protein Res., Osaka Univ.) ,  HIGASHIURA Akifumi (Inst. for Protein Res., Osaka Univ.) ,  YAMADA Yusuke (Structural Biology Res. Center, Photon Factory, Inst. of Materials Structure Sci., High Energy Accelerator Res. ...) ,  INOKUCHI Norio (School of Pharmacy, Nihon Univ.) ,  SUZUKI Mamoru (Inst. for Protein Res., Osaka Univ.)
Material： Biological and Pharmaceutical Bulletin  (Biological & Pharmaceutical Bulletin)
Volume： 37  Issue： 6  Page： 968-978 (J-STAGE)  Publication year： 2014 
JST Material Number： S0989A  ISSN： 0918-6158  CODEN： BPBLEO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： RNasePo1 ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=14A0774758&from=J-GLOBAL&jstjournalNo=S0989A") }}

JST classification (2)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Molecular structure  (EB03020Y)

Reference (58)：

• 1) Nomura H, Inokuchi N, Kobayashi H, Koyama T, Iwama M, Ohgi K, Irie M. Purification and primary structure of a new guanylic acid specific ribonuclease from Pleurotus ostreatus. J. Biochem., 116, 26-33 (1994).
• 2) Yoshida H. The ribonuclease T1 family. Methods in Enzymology. (Nicolson AW ed.) Vol. 341, Academic Press, New York, pp. 28-41 (2001).
• 3) Sugio S, Amisaki T, Ohishi H, Tomita K. Refined X-ray structure of the low pH form of ribonuclease T1-2′-guanylic acid complex at 1.9 Å resolution. J. Biochem., 103, 354-366 (1988).
• 4) Nonaka T, Mitsui Y, Irie M, Nakamura KT. Three-dimensional structure of ribonuclease Ms 3′-guanylic acid complex at 2.5 Å resolution. FEBS Lett., 283, 207-209 (1991).
• 5) Arni R, Heinemann U, Tokuoka R, Saenger W. Three-dimensional structure of the ribonuclease T1/2′-GMP complex at 1.9-A resolution. J. Biol. Chem., 263, 15358-15368 (1988).

Terms in the title (3)： 抗腫瘍活性 ,  X線 ,  結晶構造