Rchr
J-GLOBAL ID:201501023750260840   Update date: Feb. 01, 2024

Yamayoshi Asako

ヤマヨシ アサコ | Yamayoshi Asako
Affiliation and department:
Job title: Professor
Homepage URL  (2): http://www.ph.nagasaki-u.ac.jp/lab/function/index-j.htmlhttp://www.hakubi.kyoto-u.ac.jp/eng/02_mem/06yamayoshi.shtml
Research field  (3): Other ,  Biomedical engineering ,  Molecular biochemistry
Research keywords  (6): 5-methylcytosine ,  exosome ,  Antibody-oligonucleotide conjugate ,  microRNA ,  Nucleic Acid Medicine ,  Nucleic Acid Chemistry
Research theme for competitive and other funds  (23):
  • 2022 - 2026 Development of novel light-triggerd genome editing system targeting retroviral infections
  • 2020 - 2025 Biophysical Chemistry for Material Symbiosis
  • 2020 - 2025 Identification of Symbiotic Communication between Artificial Nucleic Acids and Human Immune Systems
  • 2020 - 2025 Biophysical Chemistry for Material Symbiosis
  • 2020 - 2024 病原因子の分解を誘導する分子標的型新規抗菌剤の開発基盤の構築
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Papers (84):
  • Chisato Terada, Kaho Oh, Ryutaro Tsubaki, Bun Chan, Nozomi Aibara, Kaname Ohyama, Masa-Aki Shibata, Takehiko Wada, Mariko Harada-Shiba, Asako Yamayoshi, et al. Publisher Correction: Dynamic and static control of the off-target interactions of antisense oligonucleotides using toehold chemistry. Nature communications. 2024. 15. 1. 271-271
  • Yu Mikame, Nagisa Maekawa, Soichiro Kimura, Juki Nakao, Asako Yamayoshi. Modular Synthesis of Methyl-Substituted Novel Psoralen N-Hydroxysuccinimide Esters and Evaluation of DNA Photo-Crosslinking Properties of the Corresponding Triplex-Forming Oligonucleotide Conjugates. Synlett. 2023
  • Yu Mikame, Asako Yamayoshi. Recent Advancements in Development and Therapeutic Applications of Genome-Targeting Triplex-Forming Oligonucleotides and Peptide Nucleic Acids. Pharmaceutics. 2023. 15. 10
  • Yu Mikame, Honoka Eshima, Haruki Toyama, Juki Nakao, Misaki Matsuo, Tsuyoshi Yamamoto, Yoshiyuki Hari, Jun A. Komano, and Asako Yamayoshi. Development and Crosslinking Properties of Psoralen-Conjugated Triplex-Forming Oligonucleotides as Antigene Tools Targeting Genome DNA. ChemMedChem. 2023. e202300348
  • Shota Oyama, Mao Tomita, Moeka Hata, Yu Mikame, Tsuyoshi Yamamoto, Eishi Ashihara, Asako Yamayoshi. Exosome-hijacking drug delivery system with branched arginine linker effectively deliver antisense oligonucleotides into lung adeno-carcinoma cells. Chem. Pharm. Bull. 2023
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MISC (69):
  • 中尾 樹希, 三瓶 悠, 山吉 麻子. ゲノムDNAを標的とした光駆動核酸の開発-特集 多様化するバイオテクノロジーと光技術. 光アライアンス / 光アライアンス編集委員会 編. 2023. 34. 10. 30-34
  • 三瓶悠, 山本剛史, 山吉麻子. 核酸医薬とゲノム編集技術. CLINICAL NEUROSCIENCE 「核酸医薬と神経疾患」. 2023. 41
  • Tsuyoshi Yamamoto, Asako Yamayoshi. 核酸医薬の物性制御による有効性・安全性へのアプローチ 〜核酸医薬との物質共生に向けて〜. Drug delivery system : DDS : official journal of the Japan Society of Drug Delivery System. 2022. 37. 2. 131-141
  • Asako Yamayoshi. 物質共生の観点からDDSを考える 〜「共生」と「非共生」の狭間で〜. Drug delivery system : DDS : official journal of the Japan Society of Drug Delivery System. 2022. 37. 2. 99-99
  • 和田健彦, 矢野輝, 佐藤俊幸, 稲垣雅仁, 稲垣雅仁, 西嶋政樹, 鈴木康弘, 鈴木康弘, 山本剛史, 荒木保幸, et al. Studies on Synthesis and Property of Chimeric Artificial Nucleic Acid Conjugated with DNA for Catalytic Target Vasohibin2 RNA Cleavage-1. 日本核酸医薬学会年会講演要旨集(CD-ROM). 2021. 6th
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Patents (11):
Books (14):
  • 医薬品におけるDDS技術開発と製剤への応用
    株式会社 情報機構 2021
  • 実験医学増刊 Vol.39 No.17「核酸医薬 本領を発揮する創薬モダリティ」(横田隆徳/編)
    羊土社 2021
  • 核酸科学ハンドブック
    講談社 2020 ISBN:9784065207864
  • 医薬品開発における中分子領域(核酸医薬・ペプチド医薬品)での開発戦略
    情報機構 2019
  • 中分子医薬開発に資するペプチド・核酸・糖鎖の合成・高機能化技術
    ジーエムシー出版 2018 ISBN:9784781313207
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Lectures and oral presentations  (51):
  • Development of Novel Nucleic Acid Drugs targeting non-coding Genes and Material Symbiosis
    (International Symposium for the 80th Anniversary of the Tohoku Branch of the Chemical Society of Japan (2023 Joint Meeting of the Tohoku Area Chemistry Societies) 2023)
  • Exosome-hijacking drug delivery system targeting circulating microRNAs
    (The 8th NatsJ 2023)
  • Symbiotic exosome-hijacking drug delivery system targeting circulating microRNAs
    (Transformative Research Area (B) “SPEED” Symposium -a Bridge between Chemistry and Biotechnology- 2023)
  • Development of Novel Exosome-Hijacking Drug Delivery System for Targeting Exosomal-microRNAs
    (Gordon Research Conference: Nucleosides, Nucleotides and Oligonucleotides: Chemical Biology of Nucleosides and Nucleic Acids Towards Human Therapeutics 2023)
  • Novel symbiotic exosome-hijacking drug delivery system targeting exosomal-microRNAs
    (The 7th Gratama Workshop 2023)
more...
Education (4):
  • 2000 - 2003 Kyoto Institute of Technology Graduate School of Science and Engineering Department of Biomaterial Science
  • 1998 - 2000 Kyoto Institute of Technology Graduate School of Science and Engineering Polymer Chemistry
  • 1994 - 1998 Kyoto Institute of Technology Faculty of Textile Science Polymer Chemistry
  • 1990 - 1993 TOYONAKA SENIOR HIGH SCHOOL
Professional career (1):
  • Ph.D. (Kyoto Institute of Technology)
Work history (8):
  • 2018/03 - 現在 Nagasaki University Graduate School of Biomedical Sciences Professor
  • 2021/04 - 2022/03 Osaka University School of Engineering Specially Appointed Professor
  • 2017/10 - 2021/03 JST さきがけ Sakigake Researcher
  • 2015/04 - 2018/02 Kyoto University The Hakubi Center for Advanced Research Associate Professor
  • 2007/05 - 2015/03 Kyoto Institute of Technology Department of Biomolecular Engineering Assisitant Professor
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Committee career (10):
  • 2023/06 - 現在 Journal of Controlled Release (Elsevier) Editorial Board
  • 2022/07 - 現在 日本DDS学会 評議員
  • 2022/04 - 現在 Japanese Society for Extracellular Vesicles Director
  • 2021/07 - 現在 日本ケミカルバイオロジー学会 世話人
  • 2020/09 - 現在 日本核酸化学会 役員 運営委員
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Awards (2):
  • 2022/08 - Nucleic Acids Therapeutics Society of Japan Academic Award
  • 2021/10 - 長崎大学 第6回「長崎大学未来に羽ばたく女性研究者賞」 優秀女性研究者賞
Association Membership(s) (11):
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM ,  NUCLEIC ACID CHEMISTRY OF JAPAN ,  THE NUCLEIC ACID THERAPEUTIC SOCIETY OF JAPAN ,  THE SOCIETY OF POLYMER SCIENCE, JAPAN ,  THE CHEMICAL SOCIETY OF JAPAN ,  Oligonucleotide Therapeutic Society ,  Japanese Society for Extracellular Vesicles ,  American Chemical Society ,  THE ACADEMY OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY, JAPAN ,  THE PHARMACEUTICAL SOCIETY OF JAPAN
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