Rchr
J-GLOBAL ID:201501032580866993
Update date: Nov. 26, 2024
OZAWA Manabu
オザワ マナブ | OZAWA Manabu
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Affiliation and department:
The University of Tokyo The Institute of Medical Science
About The University of Tokyo The Institute of Medical Science
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Detailed information
Homepage URL (1):
https://kaken.nii.ac.jp/d/r/80608787.ja.html
Research field (4):
Laboratory animal science
, Developmental biology
, Clinical pharmacy
, Physiology
Research keywords (9):
alternative splicing
, Sertoli cells
, spermatogonial stem cells
, testis
, spermatogenesis
, epigenetics
, meiosis
, sperm
, germ cells
Research theme for competitive and other funds (10):
2024 - 2027 Development of novel cancer therapy based on the characteristics of epigenetic leaders that are upregulated in tumors
2024 - 2026 セルトリ細胞はどのような分子経路を介して精細胞の減数分裂を制御するのか?
2021 - 2026 Development of male infertile model mice by genome editing and comprehensive study of fertilization
2020 - 2023 精細胞の分化を制御するセルトリ細胞の機能的役割の解明
2017 - 2021 Histone modifications in regulating the balance between self-renewal and differentiation of spermatogonia
2016 - 2021 Advanced Animal Model Support
2015 - 2018 The histone demethylase KDM2A regulates differentiation of spermatogonia in mice.
2013 - 2016 The histone demethylase FBXL10 regulates the proliferation of spermatogonia and ensures long-term sustainable spermatogenesis in mice
2011 - 2013 Histone demethylas Fbxl10 regulates sustainable spermatogenesis in mice.
2005 - 2007 ナノテクノロジーの応用によるブタ胚の代謝機能の解明と効率的体外生産
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Papers (87):
Takahiro Eguchi, Tohru Tezuka, Yuji Watanabe, Akane Inoue-Yamauchi, Hiroshi Sagara, Manabu Ozawa, Yuji Yamanashi. Calcium-binding protein 7 expressed in muscle negatively regulates age-related degeneration of neuromuscular junctions in mice. iScience. 2024. 27. 2. 108997-108997
Tsutomu Endo, Kiyonori Kobayashi, Takafumi Matsumura, Chihiro Emori, Manabu Ozawa, Shimpei Kawamoto, Daisuke Okuzaki, Keisuke Shimada, Haruhiko Miyata, Kentaro Shimada, et al. Multiple ageing effects on testicular/epididymal germ cells lead to decreased male fertility in mice. Communications Biology. 2024. 7. 1
Yu Ishikawa-Yamauchi, Chihiro Emori, Hideto Mori, Tsutomu Endo, Kiyonori Kobayashi, Yuji Watanabe, Hiroshi Sagara, Takeshi Nagata, Daisuke Motooka, Akinori Ninomiya, et al. Age-associated aberrations of cumulus-oocyte interaction and microfilamentous structure in the zona pellucida decline female fertility. bioRxiv. 2023
Manabu Ozawa, Hideto Mori, Tsutomu Endo, Yu Ishikawa-Yamauchi, Daisuke Motooka, Chihiro Emori, Masahiro Ikawa. Age-related decline in spermatogenic activity accompanied with endothelial cell senescence in male mice. iScience. 2023
Dan Li, Yoshikazu Johmura, Satoru Morimoto, Miyuki Doi, Keiko Nakanishi, Manabu Ozawa, Yuji Tsunekawa, Akane Inoue-Yamauchi, Hiroya Naruse, Takashi Matsukawa, et al. LONRF2 is a protein quality control ubiquitin ligase whose deficiency causes late-onset neurological deficits. Nature aging. 2023
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MISC (36):
後藤篤史, 河村真吾, 加藤皓己, 小沢学, 田口純平, 富田弘之, 今井祐記, 山田泰広, 秋山治彦. PI3K/Aktシグナルは腱再生におけるScx陽性細胞の遊走能と分化能に関与する. 日本整形外科学会雑誌. 2023. 97. 8
加藤皓己, 河村真吾, 後藤篤史, 田口純平, 小沢学, 山田泰広, 秋山治彦. 腱鞘を標識する遺伝子改変マウスの樹立. 日本整形外科学会雑誌. 2023. 97. 8
河村真吾, 伊藤謙治, 大野貴敏, 清水克時, WOLTJEN Knut, 小沢学, 戸口田淳也, 山本拓也, 秋山治彦, 山田泰広. EWS/ATF1融合遺伝子は細胞種特異的なエンハンサーに結合して明細胞肉腫を発生させる. 日本整形外科学会雑誌. 2022. 96. 3
河村真吾, 後藤篤史, 佐竹崇志, 秋山治彦, 今井祐記, 田口純平, 小沢学, 山田泰広. 腱再生とエイジング. 日本骨代謝学会学術集会プログラム抄録集(CD-ROM). 2022. 40th
河村真吾, 伊藤謙治, 大野貴敏, 清水克時, WOLTJEN Knut, 小沢学, 戸口田淳也, 山本拓也, 秋山治彦, 山田泰広. EWS/ATF1融合遺伝子は細胞種特異的なエンハンサーに結合して明細胞肉腫を発生させる. 日本整形外科学会雑誌. 2020. 94. 8
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Education (2):
1998 - 2003 University of Tsukuba
- 1998 University of Tsukuba
Professional career (1):
博士(農学) (筑波大学)
Work history (6):
2016/12 - 現在 The University of Tokyo The Institute of Medical Science
2011/01 - 2016/12 The University of Tokyo The Institute of Medical Science
2009/04 - 2011/01 University of Florida 日本学術振興会 海外特別研究員
2008/01 - 2009/04 The University of Tokyo The Institute of Medical Science
2005/04 - 2008/01 農業生物資源研究所 日本学術振興会 PD
2003/04 - 2005/03 農業生物資源研究所 特別研究員
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Committee career (2):
2024/07 - 現在 日本実験動物学会 評議委員
2022/09 - 2024/09 Society for the Study of Reproduction Virtual Education Committee
Awards (6):
2021/09 - The Society for Reproduction and Development Outstanding Paper Award
2015 - 東京大学医科学研究所創立記念シンポジウム ベストポスター賞
2014/08 - 高遠分子細胞生物学シンポジウム 優秀ポスター賞
2013 - リバネス研究費 アフィメトリクス・ジャパン賞
2009/09 - The Society for Reproduction and Development Outstanding Paper Award
2005/03 - 日本畜産学会 奨励賞
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Association Membership(s) (4):
日本実験動物学会
, Society for the Study of Reproduction
, SOCIETY FOR REPRODUCTION AND DEVELOPMENT
, THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
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