Art

J-GLOBAL ID：201502203025651802   Reference number：15A1262481

Synthesis of Azepines via a [6 + 1] Annulation of Ynenitriles with Reformatsky Reagents

Reformatsky試薬によるインニトリル類の[6+1]アンヌレーションを経たアゼピン類の合成

Author (10)： YOSHIMATSU Mitsuhiro (Gifu Univ., Gifu, JPN) ,  TANAKA Miki (Gifu Univ., Gifu, JPN) ,  FUJIMURA Yu (Gifu Univ., Gifu, JPN) ,  ITO Yukiteru (Gifu Univ., Gifu, JPN) ,  GOTO Yusuke (Gifu Univ., Gifu, JPN) ,  KOBAYASHI Yuka (Gifu Univ., Gifu, JPN) ,  WASADA Hiroaki (Gifu Univ., Gifu, JPN) ,  HATAE Noriyuki (Health Sci. Univ. Hokkaido, Hokkaido, JPN) ,  TANABE Genzoh (Kinki Univ., Osaka, JPN) ,  MURAOKA Osamu (Kinki Univ., Osaka, JPN)
Material： Journal of Organic Chemistry  (J Org Chem)
Volume： 80  Issue： 19  Page： 9480-9494  Publication year： Oct. 02, 2015 
JST Material Number： C0328A  ISSN： 0022-3263  CODEN： JOCEAH  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： chemical synthesis ,  molecular structure ,  *nitrogen heterocyclic compound ,  *carboxylate (ester) ,  Reformatskii reaction ,  hafnium complex ,  hafnium compound ,  Lewis acid catalyst ,  copper catalyst ,  copper complex ,  catalytic reaction ,  cycloaddition ,  *cyclization reaction ,  density functional method ,  *conformational energy ,  charge transfer ,  reaction mechanism ,  alkyne ,  aliphatic nitrile ,  *Azepines ,  *Pyrroles ,  *unsaturated carboxylic acid ester
Semi thesaurus term： *azepine derivative ,  *Pyrroles ,  *unsaturated ester

JST classification (4)： Nitrogen heterocycles in general  (CF07040G) ,  Alkynes  (CF03040E) ,  Cyclization reaction,ring-opening reaction  (CF02050I) ,  Configuration and conformation of molecules  (BH05022J)

Substance index (15)： 1-Tosyl-3-amino-5-phenyl-2,7-dihydro-1H-azepine-4-carboxylic acid methyl ester ,  1-Tosyl-3-amino-5-(4-methoxyphenyl)-2,7-dihydro-1H-azepine-4-carboxylic acid ethyl ester ,  1-Tosyl-3-amino-5-(p-methoxyphenyl)-2,7-dihydro-1H-azepine-4-carboxylic acid methyl ester ,  1-Tosyl-3-amino-5-(p-methoxyphenyl)-2,7-dihydro-1H-azepine-4-carboxylic acid tert-butyl ester ,  1-Tosyl-3-amino-5-(p-chlorophenyl)-2,7-dihydro-1H-azepine-4-carboxylic acid ethyl ester ,  1-Tosyl-3-amino-5-(p-chlorophenyl)-2,7-dihydro-1H-azepine-4-carboxylic acid methyl ester ,  1-Tosyl-3-amino-5-ethyl-2,7-dihydro-1H-azepine-4-carboxylic acid ethyl ester ,  1-Tosyl-3-amino-5-ethyl-2,7-dihydro-1H-azepine-4-carboxylic acid methyl ester ,  1-Tosyl-3-amino-5-phenylthio-2,7-dihydro-1H-azepine-4-carboxylic acid ethyl ester ,  1-Tosyl-3-amino-5-phenylthio-2,7-dihydro-1H-azepine-4-carboxylic acid tert-butyl ester ,  (βZ)-β-Amino-1-tosyl-3-phenyl-3-pyrroline-2-acrylic acid ethyl ester ,  (Z)-3-Amino-3-(1-tosyl-3-phenyl-2,5-dihydro-1H-pyrrole-2-yl)acrylic acid tert-butyl ester ,  (Z)-3-Amino-3-(1-tosyl-3-(p-methoxyphenyl)-2,5-dihydro-1H-pyrrole-2-yl)acrylic acid tert-butyl ester ,  (Z)-3-Amino-3-(1-tosyl-3-ethyl-2,5-dihydro-1H-pyrrole-2-yl)acrylic acid tert-butyl ester ,  (Z)-3-Amino-3-(1-tosyl-2,5-dihydro-1H-pyrrole-2-yl)acrylic acid tert-butyl ester

Terms in the title (3)： 試薬 ,  アンヌレーション ,  アゼピン類