Art

J-GLOBAL ID：201502203200012302   Reference number：15A0534876

Studies on Uniformity of the Active Ingredients in Acetaminophen Suppositories Re-solidified after Melting under High Temperature Conditions

高温条件下で溶融後に再固化させたアセトアミノフェン坐剤中の活性成分の均一性に関する研究

Author (7)： YAMAMOTO Yoshihisa (Fac. of Pharmaceutical Sciences, Teikyo Heisei Univ.) ,  FUKAMI Toshiro (Dep. of Molecular Pharmaceutics, Meiji Pharmaceutical Univ.) ,  KOIDE Tatsuo (Div. of Drugs, National Inst. of Health Sciences) ,  ONUKI Yoshinori (Dep. of Pharmaceutics, Hoshi Univ.) ,  SUZUKI Toyofumi (Lab. of Pharmaceutics, School of Pharmacy, Nihon Univ.) ,  KATORI Noriko (Div. of Drugs, National Inst. of Health Sciences) ,  TOMONO Kazuo (Lab. of Pharmaceutics, School of Pharmacy, Nihon Univ.)
Material： Chemical and Pharmaceutical Bulletin  (Chemical & Pharmaceutical Bulletin)
Volume： 63  Issue： 4  Page： 263-272 (J-STAGE)  Publication year： 2015 
JST Material Number： G0504A  ISSN： 0009-2363  CODEN： CPBTAL  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： high temperature ,...
Semi thesaurus term： drug medicine ,...

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JST classification (3)： Semi-solid preparations  (GY02040G) ,  Clinical application of antipyretic analgesics  (GW03050S) ,  Rheology in general  (BL01011R)

Substance index (1)： Acetaminophen

Reference (22)：

• 1) Walson P. D., Halvorsen M., Edge J., Casavant M. J., Kelley M. T., Clin. Ther., 35, 135-140 (2013).
• 2) de Boer A. G., Breimer D. D., Mattie H., Pronk J., Gubbens-Stibble J. M., Clin. Pharmacol. Ther., 26, 701-709 (1979).
• 3) de Boer A. G., Moolenaar F., de Leede L. G. J., Breimer D. D., Clin. Pharmacokinet., 7, 285-311 (1982).
• 4) Araki H., “Shouni No Hukuyakusido-Kanja, Kazoku Heno Setsumei,” Ishiyaku Shuppan, Tokyo, 2003, p. 33.
• 5) Ishakawa K., Takagi K., Maeda M., Okuno S., Memories of Faculty of Education and Regional Studies, University of Hukui Series V (Applied Science), 42, 1-7 (2007).

Terms in the title (7)： 溶融 ,  固化 ,  アセトアミノフェン ,  坐剤 ,  活性成分 ,  均一性 ,  研究