Art

J-GLOBAL ID：201502204913582998   Reference number：15A1025008

Efficacy of cyclosporine combination therapy for new-onset minimal change nephrotic syndrome in adults

成人における新規発症微少変化ネフローゼ症候群に関するシクロスポリン併用療法の効果

Author (15)： FUJIWARA Akira (Yokohama City Univ. School of Medicine, Dep. of Medical Sci. and Cardiorenal Medicine, Yokohama, JPN) ,  HIRAWA Nobuhito (Yokohama City Univ. Medical Center, Dep. of Nephrology and Hypertension, 45-7 Urafune-cho, Minami-ku, 232-0024 ...) ,  KOBAYASHI Yusuke (Yokohama City Univ. School of Medicine, Dep. of Medical Sci. and Cardiorenal Medicine, Yokohama, JPN) ,  YATSU Keisuke (Yokohama City Univ. School of Medicine, Dep. of Medical Sci. and Cardiorenal Medicine, Yokohama, JPN) ,  KATSUMATA Mari (Yokohama City Univ. Medical Center, Dep. of Nephrology and Hypertension, 45-7 Urafune-cho, Minami-ku, 232-0024 ...) ,  EHARA Yohsuke (Yokohama City Univ. Medical Center, Dep. of Nephrology and Hypertension, 45-7 Urafune-cho, Minami-ku, 232-0024 ...) ,  OKUYAMA Yuki (Yokohama City Univ. School of Medicine, Dep. of Medical Sci. and Cardiorenal Medicine, Yokohama, JPN) ,  YUTOH Jun (Yokohama City Univ. Medical Center, Dep. of Nephrology and Hypertension, 45-7 Urafune-cho, Minami-ku, 232-0024 ...) ,  KANEDA Tomoko (Yokohama City Univ. Medical Center, Dep. of Nephrology and Hypertension, 45-7 Urafune-cho, Minami-ku, 232-0024 ...) ,  FUJITA Megumi (Yokohama City Univ. School of Medicine, Dep. of Medical Sci. and Cardiorenal Medicine, Yokohama, JPN) ,  YAMAMOTO Yuichiro (Yokohama City Univ. Medical Center, Dep. of Nephrology and Hypertension, 45-7 Urafune-cho, Minami-ku, 232-0024 ...) ,  SAKA Sanae (Yokohama City Univ. Medical Center, Dep. of Nephrology and Hypertension, 45-7 Urafune-cho, Minami-ku, 232-0024 ...) ,  TOYA Yoshiyuki (Yokohama City Univ. School of Medicine, Dep. of Medical Sci. and Cardiorenal Medicine, Yokohama, JPN) ,  YASUDA Gen (Yokohama City Univ. Medical Center, Dep. of Nephrology and Hypertension, 45-7 Urafune-cho, Minami-ku, 232-0024 ...) ,  UMEMURA Satoshi (Yokohama City Univ. School of Medicine, Dep. of Medical Sci. and Cardiorenal Medicine, Yokohama, JPN)
Material： Clinical and Experimental Nephrology  (Clin Exp Nephrol)
Volume： 19  Issue： 2  Page： 240-246  Publication year： Apr. 2015 
JST Material Number： L3173A  ISSN： 1342-1751  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： *Nephrotic Syndrome ,...
Semi thesaurus term： Methylprednisolone pulse therapy ,...

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JST classification (1)： Drug therapy(=pharmacotherapy)for urogenital diseases  (GM05020V)

Substance index (2)： Ciclosporin ,  Prednisolone

Reference (24)：

• Imbasciati E, Gusmano R, Edefonti A, Zucchelli P, Pozzi C, Grassi C, et al. Controlled trial of methylprednisolone pulses and low dose oral prednisone for the minimal change nephrotic syndrome. Br Med J (Clin Res Ed). 1985;291:1305-8.
• Faul C, Donnelly M, Merscher-Gomez S, Chang YH, Franz S, Delfgaauw J, et al. The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A. Nat Med. 2008;14:931-8.
• Takei T, Koike M, Suzuki K, Shirota S, Itabashi M, Ohtsubo S, et al. The characteristics of relapse in adult-onset minimal-change nephrotic syndrome. Clin Exp Nephrol. 2007;11:214-7.
• Nakayama M, Katafuchi R, Yanase T, Ikeda K, Tanaka H, Fujimi S. Steroid responsiveness and frequency of relapse in adult-onset minimal change nephrotic syndrome. Am J Kidney Dis. 2002;39:503-12.
• Yorgin PD, Krasher J, Al-Uzri AY. Pulse methylprednisolone treatment of idiopathic steroid-resistant nephrotic syndrome. Pediatr Nephrol. 2001;16:245-50.

Terms in the title (5)： 成人 ,  発症 ,  微少変化ネフローゼ症候群 ,  シクロスポリン ,  併用療法