Art

J-GLOBAL ID：201502207852097187   Reference number：15A0984118

Mechanism for increased hepatic glycerol synthesis in the citrin/mitochondrial glycerol-3-phosphate dehydrogenase double-knockout mouse: Urine glycerol and glycerol 3-phosphate as potential diagnostic markers of human citrin deficiency

シトリン/ミトコンドリアグリセロール3-リン酸デヒドロゲナーゼダブルノックアウトマウスにおける肝性グルセロール合成の増強機構:ヒトシトリン欠乏の潜在的診断マーカーとしての尿グリセロール及びグリセロール3-リン酸

Author (30)： MORIYAMA Mitsuaki (Osaka Prefecture Univ., Izumisano, JPN) ,  FUJIMOTO Yuki (Kumamoto Univ., Kumamoto, JPN) ,  FUJIMOTO Yuki (Tokushima Bunri Univ., Tokushima, JPN) ,  RIKIMARU Shizuka (Tokushima Bunri Univ., Tokushima, JPN) ,  USHIKAI Miharu (Kagoshima Univ. Graduate School of Medical and Dental Sci., Kagoshima, JPN) ,  KURODA Eishi (Kagoshima Univ. Graduate School of Medical and Dental Sci., Kagoshima, JPN) ,  KAWABE Kenji (Osaka Prefecture Univ., Izumisano, JPN) ,  TAKANO Katsura (Osaka Prefecture Univ., Izumisano, JPN) ,  ASAKAWA Akihiro (Kagoshima Univ. Graduate School of Medical and Dental Sci., Kagoshima, JPN) ,  INUI Akio (Osaka Prefecture Univ., Izumisano, JPN) ,  ETO Kazuhiro (Teikyo Univ., Tokyo, JPN) ,  KADOWAKI Takashi (Univ. Tokyo, Tokyo, JPN) ,  SINASAC David S. (Univ. Calgary, Alberta, CAN) ,  OKANO Yoshiyuki (Hyogo Coll. of Medicine, Nishinomiya, JPN) ,  OKANO Yoshiyuki (Okano Children’s Clinic, Izumi, JPN) ,  YAZAKI Masahide (Shinshu Univ. School of Medicine, Matsumoto, JPN) ,  YAZAKI Masahide (Shinshu Univ., Matsumoto, JPN) ,  IKEDA Shu-ichi (Shinshu Univ. School of Medicine, Matsumoto, JPN) ,  IKEDA Shu-ichi (Shinshu Univ., Matsumoto, JPN) ,  ZHANG Chunhua (MILS International, Kanazawa, JPN) ,  SONG Yuan-Zong (Jinan Univ., Guangzhou, CHN) ,  SAKAMOTO Osamu (Tohoku Univ. Graduate School of Medicine, Sendai, JPN) ,  KURE Shigeo (Tohoku Univ. Graduate School of Medicine, Sendai, JPN) ,  MITSUBUCHI Hiroshi (Kumamoto Univ. Hospital, Kumamoto, JPN) ,  ENDO Fumio (Kumamoto Univ., Kumamoto, JPN) ,  HORIUCHIE Masahisa (Kagoshima Univ. Graduate School of Medical and Dental Sci., Kagoshima, JPN) ,  NAKAMURAA Yoichi (Osaka Prefecture Univ., Izumisano, JPN) ,  YAMAMURAB Ken-ichi (Kumamoto Univ., Kumamoto, JPN) ,  SAHEKI Takeyori (Kumamoto Univ., Kumamoto, JPN) ,  SAHEKI Takeyori (Tokushima Bunri Univ., Tokushima, JPN)
Material： Biochimica et Biophysica Acta  (BBA. Biomembranes)
Volume： 1852  Issue： 9  Page： 1787-1795  Publication year： Sep. 2015 
JST Material Number： B0207A  ISSN： 0005-2728  CODEN： BBBMBS  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： vitamin P ,  mitochondria ,  glycerophosphate dehydrogenase ,  knockout mouse ,  laboratory animal ,  *inborn errors of metabolism ,  concentration(ratio) ,  *aliphatic alcohol ,  polyol ,  inorganic acid ester ,  aliphatic ketone ,  aliphatic carboxylic acid ,  keto acid ,  nitrogen heterocyclic compound ,  quaternary ammonium ,  polynuclear aromatic compound ,  hexose ,  ketose ,  secondary alcohol ,  hydroxy acid
Semi thesaurus term： Glycerol-3-Phosphate Dehydrogenase (NAD+) ,  citrin ,  *citrin deficiency ,  double knockout mouse ,  urinary concentration

JST classification (2)： Metabolic diseases,nutritional diseases in general.  (GD05010J) ,  Animal metabolism and nutrition in general  (EJ02031R)

Substance index (6)： Glycerol ,  Glycerophasphoric acid ,  Pyruvic Acid ,  Phenazine methosulfate ,  Fructose ,  Lactic acid

Terms in the title (10)： シトリン ,  ミトコンドリア ,  グリセロール3-リン酸 ,  肝 ,  増強 ,  ヒト ,  欠乏 ,  診断マーカー ,  尿 ,  グリセロール