Art

J-GLOBAL ID：201502213332641224   Reference number：15A1013739

Identification of novel target genes specifically activated by deregulated E2F in human normal fibroblasts

ヒト正常線維芽細胞において脱制御されたE2Fによって特異的に活性化される新しい標的遺伝子の同定

Author (10)： KITAMURA Hodaka (Dep. of Biomedical Chemistry, School of Sci. and Technol., Kwansei Gakuin Univ., 2-1 Gakuen, Sanda, Hyogo, 669-1337, JPN) ,  OZONO Eiko (Signalling Lab., The Babraham Inst., Babraham Res. Campus, Cambridge, CB22 3AT, GBR) ,  IWANAGA Ritsuko (Dep. of Obstetrics and Gynecology, Univ. of Colorado School of Medicine, Anschutz Medical Campus, 12800 East 19th ...) ,  BRADFORD Andrew P. (Dep. of Obstetrics and Gynecology, Univ. of Colorado School of Medicine, Anschutz Medical Campus, 12800 East 19th ...) ,  OKUNO Junko (Dep. of Biomedical Chemistry, School of Sci. and Technol., Kwansei Gakuin Univ., 2-1 Gakuen, Sanda, Hyogo, 669-1337, JPN) ,  SHIMIZU Emi (Dep. of Biomedical Chemistry, School of Sci. and Technol., Kwansei Gakuin Univ., 2-1 Gakuen, Sanda, Hyogo, 669-1337, JPN) ,  KURAYOSHI Kenta (Dep. of Biomedical Chemistry, School of Sci. and Technol., Kwansei Gakuin Univ., 2-1 Gakuen, Sanda, Hyogo, 669-1337, JPN) ,  KUGAWA Kazuyuki (Dep. of Biomedical Chemistry, School of Sci. and Technol., Kwansei Gakuin Univ., 2-1 Gakuen, Sanda, Hyogo, 669-1337, JPN) ,  TOH Hiroyuki (Dep. of Biomedical Chemistry, School of Sci. and Technol., Kwansei Gakuin Univ., 2-1 Gakuen, Sanda, Hyogo, 669-1337, JPN) ,  OHTANI Kiyoshi (Dep. of Biomedical Chemistry, School of Sci. and Technol., Kwansei Gakuin Univ., 2-1 Gakuen, Sanda, Hyogo, 669-1337, JPN)
Material： Genes to Cells  (Genes Cells)
Volume： 20  Issue： 9  Page： 739-757  Publication year： Sep. 2015 
JST Material Number： W0935A  ISSN： 1356-9597  CODEN： GECEFL  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： fibroblast ,...
Semi thesaurus term： genetic regulation ,...

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JST classification (2)： Gene expression  (EC02040Q) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Reference (42)：

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• Chen, H.Z., Tsai, S.Y. & Leone, G. (2009) Emerging roles of E2Fs in cancer: an exit from cell cycle control. Nat. Rev. Cancer 9, 785-797.
• Dimri, G.P., Itahana, K., Acosta, M. & Campisi, J. (2000) Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14^ARF tumor suppressor. Mol. Cell. Biol. 20, 273-285.
• Dyson, N. (1998) The regulation of E2F by pRB-family proteins. Genes Dev. 12, 2245-2262.

Terms in the title (6)： ヒト ,  線維芽細胞 ,  E2F ,  活性化 ,  標的遺伝子 ,  同定