Art

J-GLOBAL ID：201502214194956622   Reference number：15A1048291

Modulation of immunological responses and amelioration of collagen-induced arthritis by the novel roxithromycin derivative 5-I

新規ロキシスロマイシン誘導体である5-Iによるコラーゲン誘導関節炎の免疫学的応答のモジュレーションと緩和

Author (13)： OTSUKI Noriko (Univ. Tokyo, Tokyo, JPN) ,  OTSUKI Noriko (National Inst. Health Sci., Tokyo, JPN) ,  IWATA Satoshi (Univ. Tokyo, Tokyo, JPN) ,  IWATA Satoshi (Juntendo Univ., Tokyo, JPN) ,  YAMADA Taketo (Keio Univ. School of Medicine, Tokyo, JPN) ,  HOSONO Osamu (Univ. Tokyo, Tokyo, JPN) ,  DANG Nam H. (Univ. Florida, FL, USA) ,  HATANO Ryo (Univ. Tokyo, Tokyo, JPN) ,  HATANO Ryo (Juntendo Univ., Tokyo, JPN) ,  OHNUMA Kei (Univ. Tokyo, Tokyo, JPN) ,  OHNUMA Kei (Juntendo Univ., Tokyo, JPN) ,  MORIMOTO Chikao (Univ. Tokyo, Tokyo, JPN) ,  MORIMOTO Chikao (Juntendo Univ., Tokyo, JPN)
Material： Modern Rheumatology  (Mod Rheumatol)
Volume： 25  Issue： 4  Page： 562-570  Publication year： Jul. 2015 
JST Material Number： L5142A  ISSN： 1439-7595  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *Arthritis ,...
Semi thesaurus term： *Collagen induced arthritis

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JST classification (1)： Basic research of anti-inflammatory drugs  (GW15010T)

Substance index (1)： (2R,3S,4S,5R,6R,8R,10S,11S,12S,13R)-6,11,12-Trihydroxy-3-[[(2R)-5β-hydroxy-4β-methoxy-4,6α-dimethyltetrahydro-2H-pyran-2β-yl]oxy]-5-[[(2S)-3α-hydroxy-4β-[(phenylsulfonyl)amino]-6β-methyltetrahydro-2H-pyran-2β-yl]oxy]-9-[[(2-methoxyethoxy)methoxy]imino]-2,4,6,8,10,12-hexamethyl-13-ethyl-14-oxacyclotetradecane-1-one

Reference (43)：

• Kudoh S, Keicho N. Diffuse panbronchiolitis. Semin Respir Criti Care Med. 2003;24(5):607-18.
• Gotfried MH. Macrolides for the treatment of chronic sinusitis, asthma, and COPD. Chest. 2004;125(2 Suppl):52S-60S.
• Park CS, Park YS, Park YJ, Cho JH, Kang JM, Kim SY. The inhibitory effects of macrolide antibiotics on bone remodeling in chronic rhinosinusitis. Otolaryngology-head and neck surgery. 2007;137(2):274-9.
• Inoue S, Nakase H, Matsuura M, Ueno S, Uza N, Kitamura H, et al. Open label trial of clarithromycin therapy in Japanese patients with Crohn's disease. J Gastroenterol Hepatol. 2007;22(7):984-8.
• Polat M, Lenk N, Yalcin B, Gur G, Tamer E, Artuz F, Alli N. Efficacy of erythromycin for psoriasis vulgaris. Clin Exp Dermatol. 2007;32(3):295-7.

Terms in the title (7)： ロキシスロマイシン ,  誘導体 ,  コラーゲン誘導関節炎 ,  免疫学 ,  応答 ,  モジュレーション ,  緩和