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J-GLOBAL ID：201502215285807056   Reference number：15A0232229

DNA損傷応答を微調節する分子機構の解明

Author (1)： NAKADA SHIN'ICHIRO (大阪大 大学院医学系研究科 細胞応答制御学)
Material： 上原記念生命科学財団研究報告集(CD-ROM)
Volume： 28  Page： ROMBUNNO.78  Publication year： Dec. 05, 2014 
JST Material Number： J1247B  ISSN： 2433-3441  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *molecular genetic phenomenon ,...
Semi thesaurus term： fine adjustment ,...

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JST classification (2)： Molecular genetics in general  (EC02010J) ,  Enzyme in general  (EB09010D)

Reference (10)：

• Escribano-Diaz, C., Orthwein, A., Fradet-Turcotte, A., Xing, M., Young, J. T., Tkac, J., Cook, M. A., Rosebrock, A. P., Munro, M., Canny, M. D., Xu, D. & Durocher, D. : A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice. Mol. Cell, 49 : 872-883, 2013.
• Hu, Y., Scully, R., Sobhian, B., Xie, A., Shestakova, E. & Livingston, D. M. : RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci. Genes. Dev., 25 : 685-700, 2011.
• Coleman, K. A. & Greenberg, R. A. : The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection. J. Biol. Chem., 286 : 13669-13680, 2011.
• Zimmermann, M., Lottersberger, F., Buonomo, S. B., Sfeir, A. & de Lange, T. : 53BP1 regulates DSB repair using Rif1 to control 5' end resection. Science, 339 : 700-704, 2013.
• Chapman, J. R., Barral, P., Vannier, J. B., Borel, V., Steger, M., Tomas-Loba, A., Sartori, A. A., Adams, I. R., Batista, F. D. & Boulton, S. J. : RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection. Mol. Cell, 49 : 858-871, 2013.

Terms in the title (3)： DNA損傷応答 ,  微調節 ,  分子