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J-GLOBAL ID：201502216051320061   Reference number：15A0954392

Okadaic acid is taken-up into the cells mediated by human hepatocytes transporter OATP1B3

オカダ酸はヒト肝細胞トランスポーターOATP1B3の媒介により細胞に取込まれる

Author (13)： IKEMA Satoshi (Div. of Food and Chemical Biology, Fac. of Fisheries, Kagoshima Univ., Kagoshima 890-0056, JPN) ,  TAKUMI Shota (Div. of Food and Chemical Biology, Fac. of Fisheries, Kagoshima Univ., Kagoshima 890-0056, JPN) ,  TAKUMI Shota (Dep. of Public Health and Environmental Medicine, The Jikei Univ. School of Medicine, Tokyo 105-8461, JPN) ,  TAKUMI Shota (Dep. of Domestic Sci., Kagoshima Women’s Coll., Kagoshima 890-8565, JPN) ,  MAEDA Yuta (Div. of Food and Chemical Biology, Fac. of Fisheries, Kagoshima Univ., Kagoshima 890-0056, JPN) ,  KURIMOTO Takashi (Div. of Food and Chemical Biology, Fac. of Fisheries, Kagoshima Univ., Kagoshima 890-0056, JPN) ,  BOHDA Shinya (Div. of Food and Chemical Biology, Fac. of Fisheries, Kagoshima Univ., Kagoshima 890-0056, JPN) ,  CHIGWECHOKHA Petros Kingstone (Div. of Food and Chemical Biology, Fac. of Fisheries, Kagoshima Univ., Kagoshima 890-0056, JPN) ,  SUGIYAMA Yasumasa (Div. of Food and Chemical Biology, Fac. of Fisheries, Kagoshima Univ., Kagoshima 890-0056, JPN) ,  SHIOZAKI Kazuhiro (Div. of Food and Chemical Biology, Fac. of Fisheries, Kagoshima Univ., Kagoshima 890-0056, JPN) ,  FURUKAWA Tatsuhiko (Dep. of Molecular Oncology, Graduate School of Medical and Dental Sciences, Kagoshima Univ., Kagoshima 890-8544, JPN) ,  FURUKAWA Tatsuhiko (Center for the Res. of Advanced Diagnosis and Therapy of Cancer, Graduate School of Medical and Dental Sciences ...) ,  KOMATSU Masaharu (Div. of Food and Chemical Biology, Fac. of Fisheries, Kagoshima Univ., Kagoshima 890-0056, JPN)
Material： Food and Chemical Toxicology  (Food Chem Toxicol)
Volume： 83  Page： 229-236  Publication year： Sep. 2015 
JST Material Number： B0937A  ISSN： 0278-6915  CODEN： FCTOD7  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,  *ion pump(organism) ,  *polypeptide ,  serine/threonine specific protein phosphatase ,  enzyme inhibition ,  shellfish toxin ,  cytotoxicity ,  antagonism ,  hepatic toxicity ,  acetal ,  spiro-compound ,  oxygen heterocyclic compound ,  olefin compound ,  secondary alcohol ,  hydroxy acid ,  cyclopeptide ,  oligopeptide
Semi thesaurus term： PP2A ,  *OATP1B1 ,  *OATP1B3

JST classification (1)： Toxicity of animal derived substances  (GZ03020U)

Substance index (2)： Okadaic acid ,  Microcystin LR

Terms in the title (5)： オカダ酸 ,  ヒト肝細胞 ,  トランスポーター ,  OATP1B3 ,  細胞