Art

J-GLOBAL ID：201502226752641142   Reference number：15A0406021

Cisplatin resistance in human lung cancer cells is linked with dysregulation of cell cycle associated proteins

ヒト肺癌細胞におけるシスプラチン耐性は,細胞周期関連タンパク質の調節不全と連動している

Author (15)： HORIBE Sayo (Lab. of Medicinal and Biochemical Analysis, Fac. of Pharmaceutical Sciences, Hiroshima International Univ., Kure ...) ,  HORIBE Sayo (Dep. of Medical Pharmaceutics, Kobe Pharmaceutical Univ., Kobe 658-8558, JPN) ,  MATSUDA Akira (Lab. of Medicinal and Biochemical Analysis, Fac. of Pharmaceutical Sciences, Hiroshima International Univ., Kure ...) ,  TANAHASHI Toshihito (Dep. of Medical Pharmaceutics, Kobe Pharmaceutical Univ., Kobe 658-8558, JPN) ,  INOUE Jun (Dep. of Medical Pharmaceutics, Kobe Pharmaceutical Univ., Kobe 658-8558, JPN) ,  KAWAUCHI Shoji (Dep. of Medical Pharmaceutics, Kobe Pharmaceutical Univ., Kobe 658-8558, JPN) ,  MIZUNO Shigeto (Dep. of Medical Pharmaceutics, Kobe Pharmaceutical Univ., Kobe 658-8558, JPN) ,  UENO Masaki (Lab. of Medicinal and Biochemical Analysis, Fac. of Pharmaceutical Sciences, Hiroshima International Univ., Kure ...) ,  TAKAHASHI Kyohei (Lab. of Medicinal and Biochemical Analysis, Fac. of Pharmaceutical Sciences, Hiroshima International Univ., Kure ...) ,  MAEDA Yusaku (Lab. of Medicinal and Biochemical Analysis, Fac. of Pharmaceutical Sciences, Hiroshima International Univ., Kure ...) ,  MAEGOUCHI Tatsuya (Lab. of Medicinal and Biochemical Analysis, Fac. of Pharmaceutical Sciences, Hiroshima International Univ., Kure ...) ,  MURAKAMI Yoshiki (Dep. of Hepatology, Graduate School of Medicine, Osaka City Univ., Osaka 545-8585, JPN) ,  YUMOTO Ryoko (Dep. of Pharmaceutics and Therapeutics, Graduate School of Biomedical and Health Sciences, Hiroshima Univ. ...) ,  NAGAI Junya (Dep. of Pharmaceutics and Therapeutics, Graduate School of Biomedical and Health Sciences, Hiroshima Univ. ...) ,  TAKANO Mikihisa (Dep. of Pharmaceutics and Therapeutics, Graduate School of Biomedical and Health Sciences, Hiroshima Univ. ...)
Material： Life Sciences  (Life Sciences including Pharmacology Letters)
Volume： 124  Page： 31-40  Publication year： Mar. 01, 2015 
JST Material Number： B0699B  ISSN： 0024-3205  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *Drug Resistance ,  *lung tumor ,  tumor cell ,  *Cell Cycle ,  *Proteins ,  *drug sensitivity ,  cross tolerance ,  A549 cell ,  carboxylate (salt) ,  platinum complex ,  flow cytometry ,  *inhibition of multiplication ,  exposure ,  cyclin-dependent kinase ,  Cyclins ,  multienzyme system ,  Phenotype ,  nitrogen heterocyclic compound ,  aromatic ketone ,  carbamate ,  sulfur heterocyclic compound ,  polynuclear aromatic compound ,  *Cisplatin resistance ,  G2/M period ,  *G2/M arrest ,  Cyclin B ,  antitumor drug ,  ammine complex ,  chloro complex ,  CDC2 Protein Kinase ,  serine-threonine kinase
Semi thesaurus term： cisplatin ,  carboplatin ,  *細胞周期関連蛋白質 ,  oxaliplatin ,  exposure to anticancer agents ,  Cdc2

JST classification (4)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Tumors(=neoplasms)of respiratory system  (GI04000G) ,  Biological function  (EB03040U) ,  Cell physiology in general  (EF02010S)

Substance index (1)： Nocodazole

Terms in the title (7)： ヒト ,  肺癌細胞 ,  シスプラチン耐性 ,  細胞周期 ,  タンパク質 ,  調節 ,  連動