Art

J-GLOBAL ID：201502249164268370   Reference number：15A0304281

Development of a robust and sensitive pyrosequencing assay for the detection of IDH1/2 mutations in gliomas

神経膠腫におけるIDH1/2変異の検出のための着実で高感度なピロシークエンシングアッセイの開発

Author (12)： ARITA Hideyuki (National Cancer Center. Hospital, Tokyo, JPN) ,  ARITA Hideyuki (National Cancer Center Res. Inst., Tokyo, JPN) ,  NARITA Yoshitaka (National Cancer Center. Hospital, Tokyo, JPN) ,  MATSUSHITA Yuko (National Cancer Center. Hospital, Tokyo, JPN) ,  FUKUSHIMA Shintaro (National Cancer Center Res. Inst., Tokyo, JPN) ,  YOSHIDA Akihiko (National Cancer Center. Hospital, Tokyo, JPN) ,  TAKAMI Hirokazu (National Cancer Center Res. Inst., Tokyo, JPN) ,  TAKAMI Hirokazu (Univ. Tokyo, Tokyo, JPN) ,  MIYAKITA Yasuji (National Cancer Center. Hospital, Tokyo, JPN) ,  OHNO Makoto (National Cancer Center. Hospital, Tokyo, JPN) ,  SHIBUI Soichiro (National Cancer Center. Hospital, Tokyo, JPN) ,  ICHIMURA Koichi (National Cancer Center Res. Inst., Tokyo, JPN)
Material： Brain Tumor Pathology  (Brain Tumor Pathol)
Volume： 32  Issue： 1  Page： 22-30  Publication year： 2015 
JST Material Number： L2617A  ISSN： 1433-7398  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： *genetic technique ,...
Semi thesaurus term： genetic variation ,...

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JST classification (3)： Tumors(=neoplasms)of nervous system  (GN04000V) ,  Diagnosis of tumors(=neoplasms)  (GE03020J) ,  Research methods in genetics  (EC01020N)

Reference (32)：

• Agarwal S, Sharma MC, Jha P, Pathak P, Suri V, Sarkar C, Chosdol K, Suri A, Kale SS, Mahapatra AK (2013) Comparative study of IDH1 mutations in gliomas by immunohistochemistry and DNA sequencing. Neuro Oncol 15:718-726
• Arita H, Narita Y, Fukushima S, Tateishi K, Matsushita Y, Yoshida A, Miyakita Y, Ohno M, Collins VP, Kawahara N, Shibui S, Ichimura K (2013) Upregulating mutations in the TERT promoter commonly occur in adult malignant gliomas and are strongly associated with total 1p19q loss. Acta Neuropathol 126:267-276
• Balss J, Meyer J, Mueller W, Korshunov A, Hartmann C, von Deimling A (2008) Analysis of the IDH1 codon 132 mutation in brain tumors. Acta Neuropathol 116:597-602
• Capper D, Zentgraf H, Balss J, Hartmann C, von Deimling A (2009) Monoclonal antibody specific for IDH1 R132H mutation. Acta Neuropathol 118:599-601
• Choi J, Lee EY, Shin KJ, Minn YK, Kim J, Kim SH (2013) IDH1 mutation analysis in low cellularity specimen: a limitation of diagnostic accuracy and a proposal for the diagnostic procedure. Pathol Res Pract 209:284-290

Terms in the title (5)： 神経膠腫 ,  IDH1 ,  変異 ,  高感度 ,  開発