Art

J-GLOBAL ID：201502268823845873   Reference number：15A0524277

Study on the inhibition of cholesterol absorption and reverse cholesterol transport by curcumin

クルクミンによるコレステロール吸収抑制・排出作用に関する研究

Author (1)： KONDO HARUMI (防衛医科大学校 内科)
Material： 浦上財団研究報告書  (Urakami Foundation Memoirs)
Volume： 22  Page： 80-88  Publication year： Mar. 2015 
JST Material Number： L0210A  ISSN： 0915-2741  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *biological absorption ,  *biological transport ,  Curcuma longa ,  polyphenol ,  hamster ,  maleness ,  HDL ,  diene ,  phenolic compound ,  phenol ether ,  enone ,  diketone ,  sterol ,  alicyclic alcohol
Semi thesaurus term： cholesterol retrograde transport ,  polyphenol ,  high density lipoprotein ,  *efflux

JST classification (2)： General  (FJ02010F) ,  Food chemistry,nutritional value  (FJ01020J)

Substance index (3)： Ezetimibe ,  Curcumin ,  Cholesterol

Reference (9)：

• Duffy D, Rader DJ (2009) Update on strategies to increase HDL quantity and function. Nat Rev Cardiol 6: 455-63.
• Xie P, Jia L, Ma Y, Ou J, Miao H, Wang N, Guo F, Yazdanyar A, Jiang XC, Yu L (2013) Ezetimibe inhibits hepatic Niemann-Pick C1-Like 1 to facilitate macrophage reverse cholesterol transport in mice. Arterioscler Thromb Vasc Biol 33: 920-5.
• Uto-Kondo H, Ayaori M, Sotherden GM, Nakaya K, Sasaki M, Yogo M, Komatsu T, Takiguchi S, Yakushiji E, Ogura M, Nishida T, Endo Y, Ikewaki K (2014) Ezetimibe enhances macrophage reverse cholesterol transport in hamsters: contribution of hepato-biliary pathway. Biochim Biophys Acta 1841: 1247-55.
• Jang EM, Choi MS, Jung UJ, Kim MJ, Kim HJ, Jeon SM, Shin SK, Seong CN, Lee MK (2008) Beneficial effects of curcumin on hyperlipidemia and insulin resistance in high-fat-fed hamsters. Metabolism 57: 1576-83.
• Kumar P, Malhotra P, Ma K, Singla A, Hedroug O, Saksena S, Dudeja PK, Gill RK, Alrefai WA (2011) SREBP2 mediates the modulation of intestinal NPC1L1 expression by curcumin. Am J Physiol Gastrointest Liver Physiol 301: G148-55.

Terms in the title (3)： クルクミン ,  コレステロール吸収 ,  研究