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J-GLOBAL ID：201502281114840414   Reference number：15A0309414

Antioxidant soybean tar Glyteer rescues T-helper-mediated downregulation of filaggrin expression via aryl hydrocarbon receptor

酸化防止剤大豆粕乾留タールは,アリール炭化水素受容体を経由してフィラグリン発現のT-ヘルパー媒介下方制御を救済する

Author (9)： TAKEI Kenjiro (Dep. of Dermatology, Kyushu Univ., Fukuoka, JPN) ,  MITOMA Chikage ,  HASHIMOTO-HACHIYA Akiko ,  UCHI Hiroshi ,  TAKAHARA Masakazu ,  TSUJI Gaku ,  KIDO-NAKAHARA Makiko ,  NAKAHARA Takeshi ,  FURUE Masutaka
Material： Journal of Dermatology  (J Dermatol)
Volume： 42  Issue： 2  Page： 171-180  Publication year： Feb. 2015 
JST Material Number： W1578A  ISSN： 0385-2407  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： *soybean cake ,...
Semi thesaurus term： NAD(P)H dehydrogenase(quinone compounds) ,...

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JST classification (3)： Basic research of pharmacology of crude drugs  (GX06020J) ,  Basic research of anti-inflammatory drugs  (GW15010T) ,  Immunological reaction in general  (ED03010T)

Substance index (1)： Benzo(a)pyrene

Reference (36)：

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• Tsuji G, Takahara M, Uchi H et al. An environmental contaminant, benzo(a)pyrene, induces oxidative stress-mediated interleukin-8 production in human keratinocytes via the aryl hydrocarbon receptor signaling pathway. J Dermatol Sci 2011; 62: 42-49.
• Kohda F, Takahara M, Hachiya A et al. Decrease of reactive oxygen species and reciprocal increase of nitric oxide in human dermal endothelial cells by Bidens pilosa extract: a possible explanation of its beneficial effect on livedo vasculopathy. J Dermatol Sci 2013; 72: 75-77.

Terms in the title (9)： 酸化防止剤 ,  大豆粕 ,  乾留 ,  タール ,  アリール炭化水素受容体 ,  フィラグリン ,  発現 ,  ヘルパー ,  下方制御