Rchr
J-GLOBAL ID:201601010630883562
Update date: Nov. 19, 2024
Nakatsu Daiki
ナカツ ダイキ | Nakatsu Daiki
Affiliation and department:
Job title:
Assistant Professor
Research field (2):
Applied molecular and cellular biology
, Other
Research theme for competitive and other funds (2):
- 2022 - 2024 M型ピルビン酸産生酵素依存的トリセルラータイトジャンクション形態形成機構の解明
- 2017 - 2018 病態モデル神経細胞創成の基盤構築
Papers (12):
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Daiki Nakatsu, Rina Kunishige, Yuki Taguchi, Naeko Shinozaki-Narikawa, Kishiko Osaka, Kayo Yokomizo, Mami Ishida, Shunsuke Takei, Shoko Yamasaki, Keita Hagiya, et al. BMP4-SMAD1/5/9-RUNX2 pathway activation inhibits neurogenesis and oligodendrogenesis in Alzheimer’s patients’ iPSCs in senescence-related conditions. Stem Cell Reports. 2023. 18. 3. 1-18
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Mikio Furuse, Daiki Nakatsu, Wendy Hempstock, Shiori Sugioka, Noriko Ishizuka, Kyoko Furuse, Taichi Sugawara, Yugo Fukazawa, Hisayoshi Hayashi. Reconstitution of functional tight junctions with individual claudin subtypes in epithelial cells. Cell Structure and Function. 2023. 48. 1. 1-17
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Yoshiyuki Noguchi, Fumi Kano, Nobuhiko Maiya, Chisako Iwamoto, Shoko Yamasaki, Yosuke Otsubo, Daiki Nakatsu, Rina Kunishige, Masayuki Murata. Microscopic image-based covariation network analysis for actin scaffold-modified insulin signaling. iScience. 2021. 24. 7. 102724-102724
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Daiki Nakatsu, Fumi Kano, Naeko Shinozaki-Narikawa, Masayuki Murata. Pyk2-dependent phosphorylation of LSR enhances localization of LSR and tricellulin at tricellular tight junctions. PLOS ONE. 2019. 14. 10. e0223300
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Yuta Horiuchi, Daiki Nakatsu, Fumi Kano, Masayuki Murata. Pyruvate kinase M1 interacts with A-Raf and inhibits endoplasmic reticulum stress-induced apoptosis by activating MEK1/ERK pathway in mouse insulinoma cells. CELLULAR SIGNALLING. 2017. 38. 212-222
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Patents (1):
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アルツハイマー疾患モデル神経細胞及びその製造方法、並びにその神経細 胞を用いたアルツハイマー病作用薬物のスクリーニング方法
Lectures and oral presentations (9):
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PKM1 regulates localization of LSR and tricellulin at tricellular tight junctions and epithelial barrier function by enhancing expression of PYK2 through the WIP1-dependent inactivation of SMAD4
(The 46th Annual Meeting of the Molecular Biology Society of Japan 2023)
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患者由来 iPS 細胞を用いたアルツハイマー依存的神経新生不全モデルの構築と構築モデル を用いた神経新生不全回復薬の同定
(第75回日本細胞生物学会大会 2023)
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PYK2はバイセルラータイトジャンクションへのトリセルラータイトジャンクション構成タン パク質の拡散を抑制する
(第73回日本細胞生物学会大会 2021)
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PYK2はLSRのリン酸化亢進を介してトリセルラータイトジャンクションへのLSRとTricellulin の局在化を促進する
(第72回日本細胞生物 学会大会 2020)
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M型ピルビン酸産生酵素PKM1は膵臓β細胞の小胞体ストレス依存的な細胞死を抑制する
(2017年度生命科学系学会合同年次大会 2017)
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Professional career (1):
Association Membership(s) (2):
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