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J-GLOBAL ID：201602242666367025   Reference number：16A0864792

Pyrrhocoricin, a proline-rich antimicrobial peptide derived from insect, inhibits the translation process in the cell-free Escherichia coli protein synthesis system

昆虫類由来の高プロリン抗菌ペプチド,Pyrrhocoricinは無細胞大腸菌蛋白質合成システムにおける翻訳過程を阻害する

Author (9)： Taniguchi Masayuki (Department of Materials Science and Technology, Graduate School of Science and Technology, Niigata University, Niigata 950-2181, Japan) ,  Taniguchi Masayuki (Center for Transdisciplinary Research, Niigata University, Niigata 950-2181, Japan) ,  Ochiai Akihito (Department of Materials Science and Technology, Graduate School of Science and Technology, Niigata University, Niigata 950-2181, Japan) ,  Kondo Hiroshi (Department of Materials Science and Technology, Graduate School of Science and Technology, Niigata University, Niigata 950-2181, Japan) ,  Fukuda Shun (Department of Materials Science and Technology, Graduate School of Science and Technology, Niigata University, Niigata 950-2181, Japan) ,  Ishiyama Yohei (Center for Fostering Innovative Leadership, Niigata University, Niigata 950-2181, Japan) ,  Saitoh Eiichi (Graduate School of Technology, Niigata Institute of Technology, Niigata 945-1195, Japan) ,  Kato Tetsuo (Department of Chemistry, Tokyo Dental College, Tokyo 101-0062, Japan) ,  Tanaka Takaaki (Department of Materials Science and Technology, Graduate School of Science and Technology, Niigata University, Niigata 950-2181, Japan)
Material： Journal of Bioscience and Bioengineering
Volume： 121  Issue： 5  Page： 591-598  Publication year： May. 2016 
JST Material Number： G0535B  ISSN： 1389-1723  CODEN： JBBIF6  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： Insecta ,...
Semi thesaurus term： *antimicrobial peptide ,...

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Author keywords (6)： Key words Pyrrhocoricin ,  Antimicrobial peptide ,  Cell-free translation system ,  Mechanism of action ,  Intracellular target ,  Inhibition of protein synthesis

JST classification (3)： Chemical synthesis  (EB03030J) ,  Drugs acting on pathogenic organisms in general  (GW17010H) ,  Molecular genetics in general  (EC02010J)

Substance index (4)： Proline ,  Streptomycin ,  Fosfomycin ,  Dodecyl sodium sulfate

Reference (51)：

• Auvynet, C. and Rosenstein, Y.: Multifunctional host defense peptides: antimicrobial peptides, the small yet big players in innate and adaptive immunity, FEBS J., 276, 6497-6508 (2009).
• Brown, K. L. and Hancock, R. E. W.: Cationic host defense (antimicrobial) peptides, Curr. Opin. Immunol., 18, 24-30 (2006).
• Hale, J. D. F. and Hancock, R. E. W.: Alternative mechanisms of action of cationic antimicrobial peptides on bacteria, Expert Rev. Anti. Infect. Ther., 5, 951-959 (2007).
• Nicolas, P.: Multifunctional host defense peptides: intracellular-targeting antimicrobial peptides, FEBS J., 276, 6483-6496 (2009).
• Nguyen, L. T., Haney, E. F., and Vogel, H. J.: The expanding scope of antimicrobial peptide strutures and their modes of action, Trends Biotechnol., 29, 464-472 (2011).

Terms in the title (8)： 昆虫類 ,  プロリン ,  抗菌ペプチド ,  細胞 ,  大腸菌蛋白質 ,  翻訳 ,  過程 ,  阻害