Art

J-GLOBAL ID：201602251058115107   Reference number：16A1080019

Formation of three-dimensional hepatic tissue by the bottom-up method using spheroids

スフェロイドを用いたボトムアップ法による三次元肝組織の形成

Author (4)： Okudaira Tatsuya (Department of Chemical Engineering, Faculty of Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan) ,  Amimoto Naoki (Department of Chemical Engineering, Faculty of Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan) ,  Mizumoto Hiroshi (Department of Chemical Engineering, Faculty of Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan) ,  Kajiwara Toshihisa (Department of Chemical Engineering, Faculty of Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan)
Material： Journal of Bioscience and Bioengineering
Volume： 122  Issue： 2  Page： 213-218  Publication year： Aug. 2016 
JST Material Number： G0535B  ISSN： 1389-1723  CODEN： JBBIF6  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： cell ,...
Semi thesaurus term： cell physiology ,...

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Author keywords (7)： Key words Tissue cell culture ,  Hollow fiber ,  Bottom-up method ,  Tissue engineering ,  Hepatocyte ,  Endothelial cell ,  Spheroid

JST classification (2)： Cell and tissue culture methods  (EA03040R) ,  Liver  (EJ06060J)

Reference (24)：

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• Bao, J., Fisher, J. E., Lillegard, J. B., Wang, W., Amiot, B., Yu, Y., Dietz, A. B., Nahmias, Y., and Nyberg, S. L.: Serum-free medium and mesenchymal stromal cells enhance functionality and stabilize integrity of rat hepatocyte spheroids, Cell Transplant., 22, 299-308 (2013).
• Ito, A., Kiyohara, T., Ijima, H., and Kamihira, M.: Enhancement of cell function through heterotypic cell-cell interactions using E-cadherin-expressing NIH3T3 cells, J. Biosci. Bioeng., 105, 679-682 (2008).
• Kidambi, S., Yarmush, R. S., Novik, E., Chao, P., Yarmush, M. L., and Nahmias, Y.: Oxygen-mediated enhancement of primary hepatocyte metabolism, functional polarization, gene expression, and drug clearance, Proc. Natl. Acad. Sci. USA, 106, 15714-15719 (2009).

Terms in the title (3)： スフェロイド ,  ボトムアップ ,  肝組織