Art

J-GLOBAL ID：201602279696526884   Reference number：16A0814844

Effect of short-term oral immunotherapy with Cry j1-galactomannan conjugate on quality of life in Japanese cedar pollinosis patients: A prospective, randomized, open-label study

日本スギ花粉症患者の生活の質に対するCry j1-ガラクトマンナン抱合体による短期口腔免疫療法の効果:前向き無作為化非盲検試験

Author (10)： Murakami Daisuke (Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan) ,  Murakami Daisuke (Department of Otorhinolaryngology, Saiseikai Fukuoka General Hospital, Fukuoka, Japan) ,  Sawatsubashi Motohiro (Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan) ,  Kikkawa Sayaka (Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan) ,  Kikkawa Sayaka (Department of Otorhinolaryngology, Saitama Medical University Hospital, Saitama, Japan) ,  Ejima Masayoshi (Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan) ,  Ejima Masayoshi (Department of Otorhinolaryngology, Kitakyushu Municipal Medical Center, Fukuoka, Japan) ,  Saito Akira (Biobusiness Propulsion Group, Biobusiness Propulsion Division, Wako Filter Technology Co., Ltd., Ibaraki, Japan) ,  Kato Akio (Department of Biological Chemistry, Yamaguchi University, Yamaguchi, Japan) ,  Komune Shizuo (Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan)
Material： Auris Nasus Larynx  (International Journal of ORL & HNS)
Volume： 43  Issue： 1  Page： 50-55  Publication year： Feb. 2016 
JST Material Number： W2247A  ISSN： 0385-8146  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： *sugi pollinosis

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Author keywords (6)： Cry j1-galactomannan conjugate ,  Japanese cedar pollinosis ,  Japan Rhinoconjunctivitis Quality of Life Questionnaire ,  Oral immunotherapy ,  Quality of life ,  Visual analog scale

JST classification (1)： Treatment for immunologic diseases,allergic diseases.  (GD04030Y)

Reference (30)：

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• Sone T, Dairiki K, Morikubo K, Shimizu K, Tsunoo H, Mori T, et al. Identification of human T cell epitopes in Japanese cypress pollen allergen, Cha o 1, elucidates the intrinsic mechanism of cross-allergenicity between Cha o 1 and Cry j 1, the major allergen of Japanese cedar pollen, at the T cell level. Clin Exp Allergy 2005;35:664-71.
• Yamada T, Saito H, Fujieda S. Present state of Japanese cedar pollinosis: the national affliction. J Allergy Clin Immunol 2014;133:632-9.
• Kanzaki S, Ogawa H, Ikeda M, Masuda T, Ogawa K. Quality of life of Japanese seasonal allergic rhinitis patients is related to timing of pollen dispersal - multicenter analysis. Acta Otolaryngol 2011;131:290-7.
• Minami Y, Shiozaki Y, Kato C, Ito M, Takeuchi N, Koyanagi M, et al. Japanese cedar pollinosis impact on work productivity, quality of life, and symptoms 2008 vs. 2009. Jpn J Rhinol 2010;49:481-9 [in Japanese].

Terms in the title (11)： 日本 ,  スギ花粉症 ,  患者 ,  生活の質 ,  ガラクトマンナン ,  抱合体 ,  短期 ,  口腔 ,  免疫療法 ,  盲 ,  試験