Art

J-GLOBAL ID：201602292956008408   Reference number：16A0800390

Determination and Identification of a Specific Marker Compound for Discriminating Shrub Chaste Tree Fruit from Agnus Castus Fruit Based on LC/MS Metabolic Analysis

LC/MS代謝分析に基づくセイヨウニンジンボク果実から低木果実を識別するための特定のマーカー化合物の決定と同定

Author (13)： Yahagi Tadahiro (School of Pharmaceutical Sciences, International University of Health and Welfare) ,  Masada Sayaka (Division of Pharmacognosy, Phytochemistry and Narcotics, National Institute of Health Sciences) ,  Oshima Naohiro (Division of Pharmacognosy, Phytochemistry and Narcotics, National Institute of Health Sciences) ,  Suzuki Ryuta (Division of Pharmacognosy, Phytochemistry and Narcotics, National Institute of Health Sciences) ,  Matsufuji Hiroshi (College of Bioresource Sciences, Nihon University) ,  Takahashi Yutaka (MS-Solutions Co., Ltd.) ,  Watanabe Masato (Medicinal Plants Eco-frontier Center, School of Pharmacy, Kumamoto University) ,  Yahara Shoji (Medicinal Plants Eco-frontier Center, School of Pharmacy, Kumamoto University) ,  Iida Osamu (Research Center for Medicinal Plant Resources, National Institute of Biomedical Innovation, Health and Nutrition) ,  Kawahara Nobuo (Research Center for Medicinal Plant Resources, National Institute of Biomedical Innovation, Health and Nutrition) ,  Maruyama Takuro (Division of Pharmacognosy, Phytochemistry and Narcotics, National Institute of Health Sciences) ,  Goda Yukihiro (Division of Drugs, National Institute of Health Sciences) ,  Hakamatsuka Takashi (Division of Pharmacognosy, Phytochemistry and Narcotics, National Institute of Health Sciences)
Material： Chemical and Pharmaceutical Bulletin  (Chemical & Pharmaceutical Bulletin)
Volume： 64  Issue： 4  Page： 305-310(J-STAGE)  Publication year： 2016 
JST Material Number： G0504A  ISSN： 0009-2363  CODEN： CPBTAL  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： LC-MS analysis ,...
Semi thesaurus term： セイヨウニンジンボク ,...

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Author keywords (12)： Shrub Chaste Tree Fruit (SCTF) ,  Agnus Castus Fruit (ACF) ,  marker compound ,  3-O-trans-feruloyl tormentic acid ,  Vitex spp. ,  multivariate analysis ,  Shrub Chaste Tree Fruit (SCTF) ,  Agnus Castus Fruit (ACF) ,  marker compound ,  3-O-trans-feruloyl tormentic acid ,  Vitex spp. ,  multivariate analysis

JST classification (1)： Crude drugs in general  (GX06010Y)

Substance index (1)： 3β-[[(E)-3-(4-Hydroxy-3-methoxyphenyl)propenoyl]oxy]-2α,19-dihydroxybauerane-28-oic acid

Reference (14)：

• 1) “The Japanese Standards for Non-Pharmacopoeial Crude Drugs (Non-JP Crude Drug Standards),” Ministry of Health, Labour, and Welfare, Japan, 2015.
• 2) “The 3rd Report on Consumption of Raw Materials for Crude Drugs in 2011 and 2012 Fiscal Years,” Crude Drugs Committee of Japan Kampo Medicines Manufacturers Association, Tokyo, 2015, p. 8.
• 3) The European Directorate for the Quality of Medicines, “The European Pharmacopoeia,” 8th edition 8.0, Strasbourg, Council of Europe, 2014, pp. 1137-1138.
• 4) European Medicines Agency, “Community herbal monograph on Vitex agnus-castus L., fructus.”: ‹http://www.ema.europa.eu/docs/en_GB/document_library/Herbal_-_Community_herbal_monograph/2011/08/WC500110099.pdf›, cited Aug. 10, 2015.
• 5) Fukahori M., Kobayashi S., Naraki Y., Sasaki T., Oka H., Seki M., Masada-Atsumi S., Hakamatsuka T., Goda Y., Chem. Pharm. Bull., 62, 379-385 (2014).

Terms in the title (8)： 代謝 ,  分析 ,  セイヨウニンジンボク ,  果実 ,  低木 ,  識別 ,  マーカー ,  同定