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J-GLOBAL ID：201702211576933347   Reference number：17A0681105

Differential X Chromosome Inactivation Patterns during the Propagation of Human Induced Pluripotent Stem Cells

ヒト誘導多能性幹細胞増幅時の異なるX染色体不活性化パターン

Author (12)： Andoh-noda Tomoko (Department of Physiology, Keio University School of Medicine, Tokyo, Japan) ,  Andoh-noda Tomoko (Faculty of Life and Environmental Sciences, Graduate Faculty of Interdisciplinary Research, University of Yamanashi, Yamanashi, Japan) ,  Akamatsu Wado (Department of Physiology, Keio University School of Medicine, Tokyo, Japan) ,  Akamatsu Wado (Center for Genomic and Regenerative Medicine, Juntendo University School of Medicine, Tokyo, Japan) ,  Miyake Kunio (Department of Health Sciences, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan) ,  Kobayashi Tetsuro (Department of Dermatology, Keio University School of Medicine, Tokyo, Japan) ,  Kobayashi Tetsuro (Present address: Dermatology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA) ,  Ohyama Manabu (Department of Dermatology, Keio University School of Medicine, Tokyo, Japan) ,  Ohyama Manabu (Present address: Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan) ,  Kurosawa Hiroshi (Faculty of Life and Environmental Sciences, Graduate Faculty of Interdisciplinary Research, University of Yamanashi, Yamanashi, Japan) ,  Kubota Takeo (Department of Epigenetic Medicine, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan) ,  Okano Hideyuki (Department of Physiology, Keio University School of Medicine, Tokyo, Japan)
Material： Keio Journal of Medicine  (Keio J Med)
Volume： 66  Issue： 1  Page： 1-8(J-STAGE)  Publication year： 2017 
JST Material Number： F0769A  ISSN： 0022-9717  CODEN： KJMEA9  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *Rett Syndrome ,...
Semi thesaurus term： genetic regulation ,...

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Author keywords (5)： induced pluripotent stem cells ,  X chromosome inactivation ,  epigenetic memory ,  reprogramming ,  Rett syndrome

JST classification (2)： Congenital diseases,deformities in general.  (GD03010V) ,  Gene manipulation  (EC02050B)

Reference (52)：

• 1. Takahashi K,Yamanaka S: Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006; 126: 663-676.
• 2. Takahashi K,Tanabe K,Ohnuki M,Narita M,Ichisaka T,Tomoda K,Yamanaka S: Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007; 131: 861-872.
• 3. Yu J,Vodyanik MA,Smuga-Otto K,Antosiewicz-Bourget J,Frane JL,Tian S,Nie J,Jonsdottir GA,Ruotti V,Stewart R,Slukvin II,Thomson JA: Induced pluripotent stem cell lines derived from human somatic cells. Science 2007; 318: 1917-1920.
• 4. Mayshar Y,Ben-David U,Lavon N,Biancotti JC,Yakir B,Clark AT,Plath K,Lowry WE,Benvenisty N: Identification and classification of chromosomal aberrations in human induced pluripotent stem cells. Cell Stem Cell 2010; 7: 521-531.
• 5. Taapken SM,Nisler BS,Newton MA,Sampsell-Barron TL,Leonhard KA,McIntire EM,Montgomery KD: Karotypic abnormalities in human induced pluripotent stem cells and embryonic stem cells. Nat Biotechnol 2011; 29: 313-314.

Terms in the title (5)： ヒト ,  誘導 ,  多能性幹細胞 ,  増幅 ,  X染色体不活性化