Art

J-GLOBAL ID：201702214506552888   Reference number：17A1213771

Both polarity and aromatic ring in the side chain of tryptophan 246 are involved in binding activity of Vibrio vulnificus hemolysin to target cells

トリプトファン246の側鎖における極性と芳香環の両方が標的細胞へのVibrio vulnificus溶血素の結合活性に関与する【Powered by NICT】

Author (5)： Kashimoto Takashige (Laboratory of Veterinary Public Health, School of Veterinary Medicine, Kitasato University, Higashi 23-35-1, Towada, Aomori, Japan) ,  Akita Tomoe (Laboratory of Veterinary Public Health, School of Veterinary Medicine, Kitasato University, Higashi 23-35-1, Towada, Aomori, Japan) ,  Kado Takehiro (Laboratory of Veterinary Public Health, School of Veterinary Medicine, Kitasato University, Higashi 23-35-1, Towada, Aomori, Japan) ,  Yamazaki Kohei (Laboratory of Veterinary Public Health, School of Veterinary Medicine, Kitasato University, Higashi 23-35-1, Towada, Aomori, Japan) ,  Ueno Shunji (Laboratory of Veterinary Public Health, School of Veterinary Medicine, Kitasato University, Higashi 23-35-1, Towada, Aomori, Japan)
Material： Microbial Pathogenesis  (Microb Pathog)
Volume： 109  Page： 71-77  Publication year： 2017 
JST Material Number： T0489A  ISSN： 0882-4010  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Vibrio vulnificus secretes a h...

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Thesaurus term： CHO cell ,  Cell Membrane ,  *hemolysin ,  toxin ,  pore ,  *side chain ,  cytotoxicity ,  *polarity ,  wild type ,  oligomer ,  cytolysin ,  cell lysis ,  *Vibrio vulnificus ,  *Vibrio ,  Endomembrane system ,  *microorganism ,  nitrogen heterocyclic compound ,  polynuclear aromatic compound
Semi thesaurus term： *Vibrio , 【Automatic Indexing@JST】

Author keywords (4)： Vibrio vulnificus ,  Hemolysin ,  Domain ,  Binding

JST classification (2)： Toxicity of microorganism derived substances  (GZ03030F) ,  Microorganism biochemistry  (EG03020N)

Substance index (1)： Indole

Terms in the title (7)： トリプトファン ,  側鎖 ,  極性 ,  芳香環 ,  Vibrio ,  溶血素 ,  結合活性