Art

J-GLOBAL ID：201702215580202786   Reference number：17A0087637

Pregnancy outcomes of patients with paroxysmal nocturnal hemoglobinuria treated with eculizumab: a Japanese experience and updated review

エクリズマブで治療した発作性夜間血色素尿症患者の妊娠結果:日本人の経験と最新のレビュー

Author (30)： Miyasaka Naoyuki (Department of Pediatrics, Perinatal and Maternal Medicine, Graduate School of Tokyo Medical and Dental University (TMDU), Tokyo, Japan) ,  Miyasaka Naoyuki (Working Group for Pregnancy in PNH, The Japan PNH Study Group, Tokyo, Japan) ,  Miura Osamu (Department of Hematology, Graduate School of Tokyo Medical and Dental University, Tokyo, Japan) ,  Miura Osamu (Working Group for Pregnancy in PNH, The Japan PNH Study Group, Tokyo, Japan) ,  Kawaguchi Tatsuya (Departments of Hematology and Infectious Diseases, Kumamoto University Hospital, Kumamoto, Japan) ,  Kawaguchi Tatsuya (Working Group for Pregnancy in PNH, The Japan PNH Study Group, Tokyo, Japan) ,  Arima Nobuyoshi (Department of Hematology, Medical Research Institute Kitano Hospital, Osaka, Japan) ,  Arima Nobuyoshi (Working Group for Pregnancy in PNH, The Japan PNH Study Group, Tokyo, Japan) ,  Morishita Eriko (Department of Clinical Laboratory Science, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan) ,  Morishita Eriko (Working Group for Pregnancy in PNH, The Japan PNH Study Group, Tokyo, Japan) ,  Usuki Kensuke (Department of Hematology, NTT Medical Center Tokyo, Tokyo, Japan) ,  Usuki Kensuke (Working Group for Pregnancy in PNH, The Japan PNH Study Group, Tokyo, Japan) ,  Morita Yasuyoshi (Division of Hematology and Rheumatology, Department of Internal Medicine, Kinki University Faculty of Medicine, Osaka-Sayama, Osaka, Japan) ,  Morita Yasuyoshi (Working Group for Pregnancy in PNH, The Japan PNH Study Group, Tokyo, Japan) ,  Nishiwaki Kaichi (Department of Oncology and Haematology, Jikei University Kashiwa Hospital, Kashiwa, Chiba, Japan) ,  Nishiwaki Kaichi (Working Group for Pregnancy in PNH, The Japan PNH Study Group, Tokyo, Japan) ,  Ninomiya Haruhiko (Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan) ,  Ninomiya Haruhiko (Working Group for Pregnancy in PNH, The Japan PNH Study Group, Tokyo, Japan) ,  Gotoh Akihiko (Division of Hematology, First Department of Internal Medicine, Tokyo Medical University, Tokyo, Japan) ,  Gotoh Akihiko (Working Group for Pregnancy in PNH, The Japan PNH Study Group, Tokyo, Japan) ,  Imashuku Shinsaku (Division of Hematology, Takasago-Seibu Hospital, Takasago, Japan) ,  Imashuku Shinsaku (Working Group for Pregnancy in PNH, The Japan PNH Study Group, Tokyo, Japan) ,  Urabe Akio (Department of Hematology, NTT Medical Center Tokyo, Tokyo, Japan) ,  Urabe Akio (Working Group for Pregnancy in PNH, The Japan PNH Study Group, Tokyo, Japan) ,  Shichishima Tsutomu (Department of Cardiology and Hematology, Fukushima Medical University, Fukushima, Japan) ,  Shichishima Tsutomu (Working Group for Pregnancy in PNH, The Japan PNH Study Group, Tokyo, Japan) ,  Nishimura Jun-ichi (Department of Hematology and Oncology, Osaka University Graduate School of Medicine, Osaka, Japan) ,  Nishimura Jun-ichi (Working Group for Pregnancy in PNH, The Japan PNH Study Group, Tokyo, Japan) ,  Kanakura Yuzuru (Department of Hematology and Oncology, Osaka University Graduate School of Medicine, Osaka, Japan) ,  Kanakura Yuzuru (Working Group for Pregnancy in PNH, The Japan PNH Study Group, Tokyo, Japan)
Material： International Journal of Hematology  (Int J Hematol)
Volume： 103  Issue： 6  Page： 703-712  Publication year： Jun. 2016 
JST Material Number： F0888A  ISSN： 0925-5710  CODEN： IJHEEY  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： *urologic disease ,...
Semi thesaurus term： *Paroxysmal nocturnal hemoglobinuria ,...

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Author keywords (3)： Paroxysmal nocturnal hemoglobinuria ,  Pregnancy ,  Eculizumab

JST classification (1)： Clinical hematology in general  (GK01030Y)

Reference (32)：

• Miyata T, Takeda J, Iida Y, Yamada N, Inoue N, Takahashi M, et al. The cloning of PIG-A, a component in the early step of GPI-anchor biosynthesis. Science. 1993;259(5099):1318-20.
• Miyata T, Yamada N, Iida Y, Nishimura J, Takeda J, Kitani T, et al. Abnormalities of PIG-A transcripts in granulocytes from patients with paroxysmal nocturnal hemoglobinuria. N Engl J Med. 1994;330(4):249-55.
• Takeda J, Miyata T, Kawagoe K, Iida Y, Endo Y, Fujita T, et al. Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria. Cell. 1993;73(4):703-11.
• Parker C, Omine M, Richards S, Nishimura J, Bessler M, Ware R, et al. Diagnosis and management of paroxysmal nocturnal hemoglobinuria. Blood. 2005;106(12):3699-709.
• Brodsky RA. How I treat paroxysmal nocturnal hemoglobinuria. Blood. 2009;113(26):6522-7.

Terms in the title (8)： エクリズマブ ,  治療 ,  発作性夜間血色素尿症 ,  患者 ,  妊娠結果 ,  日本人 ,  経験 ,  レビュー