Art

J-GLOBAL ID：201702218021228518   Reference number：17A0972327

SAMP8 mice as a neuropathological model of accelerated brain aging and dementia: Toshio Takeda’s legacy and future directions

脳老化促進および認知症の神経病理学的モデルとしてのSAMP8マウス:Toshio Takedaの遺産と将来の方向性

Author (15)： Akiguchi Ichiro (Center of Neurological and Cerebrovascular Diseases, Koseikai Takeda Hospital, Kyoto, Japan) ,  Akiguchi Ichiro (Department of Health Science, Kyoto Koka Women’s University, Kyoto, Japan) ,  Pallas Merce (Pharmacology Section and Institute of Neuroscience, University of Barcelona, Barcelona, Spain) ,  Budka Herbert (Institute of Neuropathology, University Hospital Zurich, Zurich, Switzerland) ,  Akiyama Haruhiko (Department of Clinical Research, Yokohama Brain and Spine Center, Yokohama, Japan) ,  Ueno Masaki (Department of Pathology and Host Defence, Faculty of Medicine, Kagawa University, Takamatsu, Japan) ,  Han Jingxian (The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China) ,  Yagi Hideo (Center of Neurological and Cerebrovascular Diseases, Koseikai Takeda Hospital, Kyoto, Japan) ,  Nishikawa Tomohumi (Department of Health Science, Kyoto Koka Women’s University, Kyoto, Japan) ,  Chiba Yoichi (Department of Pathology and Host Defence, Faculty of Medicine, Kagawa University, Takamatsu, Japan) ,  Sugiyama Hiroshi (National Hospital Organization Utano Hospital, Kyoto, Japan) ,  Takahashi Ryoya (Department of Biochemistry, Faculty of Pharmaceutical Sciences, Toho University, Chiba, Japan) ,  Unno Keiko (School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan) ,  Higuchi Keiichi (Department of Aging Biology, Institute of Pathogenesis and Disease Prevention, Shinshu University Graduate School of Medicine, Matsumoto, Japan) ,  Hosokawa Masanori (Institute for Developmental Research, Aichi Human Service Center, Nagoya, Japan)
Material： Neuropathology (Web)  (日本神経病理学会総会学術研究会プログラム・抄録集(Web))
Volume： 37  Issue： 4  Page： 293-305  Publication year： 2017 
JST Material Number： U0508A  ISSN： 1440-1789  Document type： Article
Article type： 文献レビュー  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *Mus musculus ,...
Semi thesaurus term： Astrogliosis

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Author keywords (5)： Alzheimer’s disease ,  brainstem ,  hippocampus ,  SAMP8 ,  senescence-accelerated model

JST classification (2)： Laboratry organisms  (EA03070Y) ,  Basic neurology  (GN01020W)

Reference (89)：

• Takeda T, Hosokawa M, Higuchi K. Senescence-accelerated mouse (SAM): A novel murine model of accelerated senescence. J Amer Geriatr Soc 1991; 39: 911-919.
• Takeda T, Hosokawa M, Higuchi K, Hosono M, Akiguchi I, Katoh H. A novel murine model of aging, Senescence-Accelerated Mouse (SAM). Arch Gerontol Geriatr 1994; 19: 185-192.
• Takeda T, Akiguchi I. Behavioral and neuropathological studies on strains of SAM with spontaneous age-related deficits in learning and memory. Neuropathology 1991; (Suppl 4): 371-374.
• Miyamoto M, Kiyota Y, Tamazaki N et al. Age-related changes in learning and memory in the senescence-accelerated mouse (SAM). Physiol Behav 1986; 45: 393-406.
• Yagi H, Katoh S, Akiguchi I, Takeda T. Age-related deterioration of ability of acquisition in memory and learning in senescence accelerated mouse: SAM-P/8 as an animal modal of disturbance in recent memory. Brain Res 1988; 474: 86-93.

Terms in the title (8)： 脳老化 ,  促進 ,  認知症 ,  神経病理学 ,  モデル ,  SAMP8マウス ,  将来 ,  方向性