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J-GLOBAL ID：201702220028803791   Reference number：17A1099785

The SETD8/PR-Set7 Methyltransferase Functions as a Barrier to Prevent Senescence-Associated Metabolic Remodeling

老化関連代謝リモデリングを予防するための障壁としてのSETD8/PR集合7メチルトランスフェラーゼ機能【Powered by NICT】

Author (9)： Tanaka Hiroshi (Department of Medical Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto 860-0811, Japan) ,  Takebayashi Shin-ichiro (Department of Medical Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto 860-0811, Japan) ,  Sakamoto Akihisa (Department of Medical Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto 860-0811, Japan) ,  Igata Tomoka (Department of Medical Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto 860-0811, Japan) ,  Nakatsu Yuko (Department of Medical Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto 860-0811, Japan) ,  Saitoh Noriko (Department of Medical Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto 860-0811, Japan) ,  Hino Shinjiro (Department of Medical Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto 860-0811, Japan) ,  Nakao Mitsuyoshi (Department of Medical Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto 860-0811, Japan) ,  Nakao Mitsuyoshi (Core Research for Evolutional Science and Technology (CREST), Japan Agency for Medical Research and Development (AMED), Tokyo 100-0004, Japan)
Material： Cell Reports
Volume： 18  Issue： 9  Page： 2148-2161  Publication year： 2017 
JST Material Number： W3124A  ISSN： 2211-1247  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Cellular senescence is an irre...

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Thesaurus term： cell aging ,  *metabolism ,  chromatin ,  ribosomal protein ,  gene ,  rRNA ,  Rb protein ,  oncogene ,  *methyltransferase ,  cyclin-dependent kinase ,  mitochondria
Semi thesaurus term： 複製老化 ,  ヒストンH4 ,  腫瘍抑制 ,  *リモデリング , 【Automatic Indexing@JST】

Author keywords (5)： SETD8/PR-Set7 ,  H4K20 methylation ,  senescence-associated metabolic remodeling ,  nucleolus ,  mitochondria

JST classification (1)： Cell physiology in general  (EF02010S)

Terms in the title (8)： 老化 ,  代謝 ,  リモデリング ,  予防 ,  障壁 ,  Pr ,  集合 ,  メチルトランスフェラーゼ