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J-GLOBAL ID：201702221303616248   Reference number：17A0386485

¹³C-metabolic flux analysis for mevalonate-producing strain of Escherichia coli

メバロン酸産生Escherichia coli株の¹³C-代謝フラックス解析

Author (6)： Wada Keisuke (Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University, 1-5 Yamadaoka, Suita, Osaka 565-0871, Japan) ,  Toya Yoshihiro (Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University, 1-5 Yamadaoka, Suita, Osaka 565-0871, Japan) ,  Banno Satomi (Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University, 1-5 Yamadaoka, Suita, Osaka 565-0871, Japan) ,  Yoshikawa Katsunori (Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University, 1-5 Yamadaoka, Suita, Osaka 565-0871, Japan) ,  Matsuda Fumio (Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University, 1-5 Yamadaoka, Suita, Osaka 565-0871, Japan) ,  Shimizu Hiroshi (Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University, 1-5 Yamadaoka, Suita, Osaka 565-0871, Japan)
Material： Journal of Bioscience and Bioengineering
Volume： 123  Issue： 2  Page： 177-182  Publication year： Feb. 2017 
JST Material Number： G0535B  ISSN： 1389-1723  CODEN： JBBIF6  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *Escherichia coli ,...
Semi thesaurus term： Metabolic flux analysis

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Author keywords (7)： Key words ¹³C-metabolic flux analysis ,  Mevalonate ,  Escherichia coli ,  [1-¹³C] glucose ,  Flux distribution ,  Redox balance ,  Flux balance analysis

JST classification (2)： Microbial metabolite production  (FK03020A) ,  Gene manipulation  (EC02050B)

Substance index (1)： Mevalonic Acid

Reference (29)：

• Martin, V. J., Pitera, D. J., Withers, S. T., Newman, J. D., and Keasling, J. D.: Engineering a mevalonate pathway in Escherichia coli for production of terpenoids, Nat. Biotechnol., 21, 796-802 (2003).
• Haratake, A., Ikenaga, K., Katoh, N., Uchiwa, H., Hirano, S., and Yasuno, H.: Topical mevalonic acid stimulates de novo cholesterol synthesis and epidermal permeability barrier homeostasis in aged mice, J. Invest. Dermatol., 114, 247-252 (2000).
• Wang, C., Yoon, S. H., Shah, A. A., Chung, Y. R., Kim, J. Y., Choi, E. S., Keasling, J. D., and Kim, S. W.: Farnesol production from Escherichia coli by harnessing the exogenous mevalonate pathway, Biotechnol. Bioeng., 107, 421-429 (2010).
• Yoon, S. H., Lee, S. H., Das, A., Ryu, H. K., Jang, H. J., Kim, J. Y., Oh, D. K., Keasling, J. D., and Kim, S. W.: Combinatorial expression of bacterial whole mevalonate pathway for the production of beta-carotene in E. coli, J. Biotechnol., 140, 218-226 (2009).
• Miziorko, H. M.: Enzymes of the mevalonate pathway of isoprenoid biosynthesis, Arch. Biochem. Biophys., 505, 131-143 (2011).

Terms in the title (4)： メバロン酸 ,  Escherichia ,  株 ,  代謝フラックス解析