Art

J-GLOBAL ID：201702228043323845   Reference number：17A1837216

SYNTHESIS OF 8,9-DIHYDROPYRIMIDO[4,5-e][1,4]OXAZEPIN-7(5H)-ONES BY THE REACTION OF 1-(4-CHLOROPYRIMIDIN-5-YL)ALKAN-1-OLS WITH N-ALKYLGLYCINES

1-(4-クロロピリミジン-5-イル)アルカン-1-オールとN-アルキルグリシンとの反応による8,9-ジヒドロピリミド[4,5-e][1,4]オキサゼピン-7(5H)-オン類の合成

Author (5)： KOBAYASHI Kazuhiro (Tottori Univ., Tottori, JPN) ,  NOGI Takashi (Tottori Univ., Tottori, JPN) ,  TSUNOMORI Yuka (Tottori Univ., Tottori, JPN) ,  HIYOSHI Hidetaka (KUMIAI CHEMICAL IND. CO., LTD., Tokyo, JPN) ,  UMEZU Kazuto (KUMIAI CHEMICAL IND. CO., LTD., Tokyo, JPN)
Material： Heterocycles  (International Journal for Reviews and Communications in Heterocyclic Chemistry)
Volume： 94  Issue： 11  Page： 2087-2094  Publication year： Nov. 01, 2017 
JST Material Number： S0966A  ISSN： 0385-5414  CODEN： HTCYAM  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： chemical synthesis ,  substitution reaction ,  *lactonization ,  secondary alcohol ,  hydroxy acid ,  *lactone ,  *nitrogen heterocyclic compound ,  amino acid
Semi thesaurus term： Oxazepines ,  Glycine Derivatives ,  Pyrimidines

JST classification (1)： Seven-membered heterocyclic compounds  (CF07110I)

Substance index (12)： 2-Methylthio-4,6-dichloropyrimidine ,  2-(Methylthio)-4-chloro-5-(3,4-dimethoxyphenyl)-9-methyl-8,9-dihydropyrimido[4,5-e][1,4]oxazepine-7(5H)-one ,  2-(Methylthio)-4-chloro-5-(3-thienyl)-9-methyl-8,9-dihydropyrimido[4,5-e][1,4]oxazepine-7(5H)-one ,  2-(Methylthio)-4-chloro-5-(3-methylphenyl)-9-methyl-8,9-dihydropyrimido[4,5-e][1,4]oxazepine-7(5H)-one ,  2-(Methylthio)-4-chloro-5-(4-chlorophenyl)-9-methyl-8,9-dihydropyrimido[4,5-e][1,4]oxazepine-7(5H)-one ,  2-(Methylthio)-4-chloro-5-(4-methoxyphenyl)-9-ethyl-8,9-dihydropyrimido[4,5-e][1,4]oxazepine-7(5H)-one ,  2-(Methylthio)-4-chloro-5-(4-methoxyphenyl)-9-methyl-8,9-dihydropyrimido[4,5-e][1,4]oxazepine-7(5H)-one ,  2-(Methylthio)-4-chloro-5-isopropyl-9-methyl-8,9-dihydropyrimido[4,5-e][1,4]oxazepine-7(5H)-one ,  2-(Methylthio)-4-chloro-5-ethyl-9-methyl-8,9-dihydropyrimido[4,5-e][1,4]oxazepine-7(5H)-one ,  2-(Methylthio)-4-chloro-5-phenyl-9-ethyl-8,9-dihydropyrimido[4,5-e][1,4]oxazepine-7(5H)-one ,  2-(Methylthio)-4-chloro-5-phenyl-9-methyl-8,9-dihydropyrimido[4,5-e][1,4]oxazepine-7(5H)-one ,  α-Phenyl-2-(methylthio)-4,6-dichloropyrimidine-5-methanol

Reference (4)：

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Terms in the title (2)： 4-クロロピリミジン ,  アルカン