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J-GLOBAL ID：201702231257818125   Reference number：17A0686198

Overexpression of Sp7 in odontoblasts results in dentinogenesis imperfecta due to the inhibition of odontoblast maturation

象牙質芽細胞のSp7過発現は象牙質芽細胞成熟の抑制により象牙質形成不全症を起こす

Author (4)： Miyazaki Toshihiro (Department of Cell Biology, Unit of Basic Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8588, Japan) ,  Inoue Maaya (Department of Cell Biology, Unit of Basic Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8588, Japan) ,  Baba Tomomi T. (Department of Oral Molecular Biology, Unit of Basic Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan) ,  Komori Toshihisa (Department of Cell Biology, Unit of Basic Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8588, Japan)
Material： Journal of Oral Biosciences  (J Oral Biosci)
Volume： 59  Issue： 2  Page： 113-120  Publication year： May. 2017 
JST Material Number： W2309A  ISSN： 1349-0079  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *blast cell ,...
Semi thesaurus term： *dentin hypoplasia ,...

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Author keywords (5)： Sp7 ,  Odontoblast differentiation ,  Dentin matrix protein ,  DSP ,  Nestin

JST classification (3)： Basic dentistry(= odontology)  (GT01020O) ,  Biological function  (EB03040U) ,  Cell physiology in general  (EF02010S)

Reference (23)：

• Thesleff I. Epithelial-mesenchymal signalling regulating tooth morphogenesis. J Cell Sci 2003;116:1647-8.
• Balic A, Thesleff I. Tissue interactions regulating tooth development and renewal. Curr Top Dev Biol 2015;115:157-86.
• Kawashima N, Okiji T. Odontoblasts: specialized hard-tissue-forming cells in the dentin-pulp complex. Congenit Anom (Kyoto) 2016;56:144-53.
• Komori T, Yagi H, Nomura S, Yamaguchi A, Sasaki K, Deguchi K, Shimizu Y, Bronson RT, Gao YH, Inada M, Sato M, Okamoto R, Kitamura Y, Yoshiki S, Kishimoto T. Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 1997;89:755-64.
• Komori T. Regulation of osteoblast and odontoblast differentiation by RUNX2. J Oral Biosci 2010;52:22-5.

Terms in the title (4)： 象牙質芽細胞 ,  発現 ,  成熟 ,  象牙質形成不全症