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J-GLOBAL ID：201702233608940147   Reference number：17A0968372

Conformational transition of DNA by dinuclear Pt(II) complexes causes cooperative inhibition of gene expression

二核Pt(II)錯体によるDNAの立体配座転移は遺伝子発現の協同的阻害を引き起こす【Powered by NICT】

Author (5)： Shimizu Yuta (Faculty of Life and Medical Sciences, Doshisha University, Kyotanabe 610-0321, Japan) ,  Yoshikawa Yuko (Faculty of Life and Medical Sciences, Doshisha University, Kyotanabe 610-0321, Japan) ,  Kenmotsu Takahiro (Faculty of Life and Medical Sciences, Doshisha University, Kyotanabe 610-0321, Japan) ,  Komeda Seiji (Faculty of Pharmaceutical Sciences, Suzuka University of Medical Science, Suzuka 513-8670, Japan) ,  Yoshikawa Kenichi (Faculty of Life and Medical Sciences, Doshisha University, Kyotanabe 610-0321, Japan)
Material： Chemical Physics Letters  (Chem Phys Lett)
Volume： 678  Page： 123-129  Publication year： 2017 
JST Material Number： B0824A  ISSN： 0009-2614  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Recently, it was reported that...

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Thesaurus term： *steric conformation ,  *gene expression ,  atomic force microscope ,  *complex (compound) ,  in vitro experiment ,  cation ,  higher order structure ,  *DNA ,  antitumor drug ,  *conformational transition ,  Fluorescence ,  genomic DNA ,  *molecular genetic phenomenon
Semi thesaurus term： 抑制効果 , 【Automatic Indexing@JST】

Author keywords (4)： Higher-order structure of DNA ,  Single DNA observation ,  Anticancer drug ,  Cooperativity

JST classification (1)： Electronic structure of molecules  (BH05010Q)

Terms in the title (8)： 核 ,  Pt ,  錯体 ,  DNA ,  立体配座転移 ,  遺伝子発現 ,  協同 ,  阻害