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J-GLOBAL ID：201702234412328465   Reference number：17A1714306

Quantitative analysis of O-GlcNAcylation in combination with isobaric tag labeling and chemoenzymatic enrichment

等圧タグ標識および化学酵素的濃縮と組み合わせたO-GlcNAc化の定量的解析【Powered by NICT】

Author (4)： Tsumoto Hiroki (Research Team for Mechanism of Aging, Tokyo Metropolitan Institute of Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo 173-0015, Japan) ,  Akimoto Yoshihiro (Department of Anatomy, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka-shi, Tokyo 181-8611, Japan) ,  Endo Tamao (Research Team for Mechanism of Aging, Tokyo Metropolitan Institute of Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo 173-0015, Japan) ,  Miura Yuri (Research Team for Mechanism of Aging, Tokyo Metropolitan Institute of Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo 173-0015, Japan)
Material： Bioorganic & Medicinal Chemistry Letters  (Bioorg Med Chem Lett)
Volume： 27  Issue： 22  Page： 5022-5026  Publication year： 2017 
JST Material Number： W0248A  ISSN： 0960-894X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Protein O-GlcNAcylation regula...

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Thesaurus term： biological sample ,  *quantitative analysis ,  *enzyme ,  Michael reaction ,  peptide ,  Proteins ,  desorption ,  Acylation ,  Quantitative proteomics ,  Biological Processes ,  *O-GlcNAc ,  aliphatic alcohol ,  thiol ,  diol ,  secondary alcohol

Author keywords (5)： O-GlcNAc ,  Enrichment ,  Thiol-alkyne ,  Thiol-disulfide exchange ,  iTRAQ

JST classification (2)： Peptides  (CF10080G) ,  Enzyme in general  (EB09010D)

Substance index (1)： Dithiothreitol

Terms in the title (8)： 等圧 ,  タグ ,  標識 ,  化学 ,  酵素 ,  濃縮 ,  O-GlcNAc ,  定量的解析