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J-GLOBAL ID：201702243652171876   Reference number：17A1970005

Determination of poor prognostic immune features of tumour microenvironment in non-smoking patients with lung adenocarcinoma

肺腺癌の非喫煙患者における腫瘍微小環境の予後不良免疫特徴の決定【Powered by NICT】

Author (21)： Kinoshita Tomonari (Division of Cellular Signaling, Institute for Advanced Medical Research, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 1608582, Japan) ,  Kinoshita Tomonari (Division of General Thoracic Surgery, Department of Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 1608582, Japan) ,  Kudo-Saito Chie (Division of Molecular & Cellular Medicine, Group for Translational Research, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo, Tokyo 1040045, Japan) ,  Muramatsu Reiko (Division of Cellular Signaling, Institute for Advanced Medical Research, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 1608582, Japan) ,  Fujita Tomonobu (Division of Cellular Signaling, Institute for Advanced Medical Research, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 1608582, Japan) ,  Saito Miyuki (Division of Cellular Signaling, Institute for Advanced Medical Research, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 1608582, Japan) ,  Nagumo Haruna (Division of Cellular Signaling, Institute for Advanced Medical Research, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 1608582, Japan) ,  Sakurai Toshiharu (Division of Cellular Signaling, Institute for Advanced Medical Research, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 1608582, Japan) ,  Noji Shinobu (Division of Cellular Signaling, Institute for Advanced Medical Research, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 1608582, Japan) ,  Takahata Emi (Division of Cellular Signaling, Institute for Advanced Medical Research, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 1608582, Japan) ,  Yaguchi Tomonori (Division of Cellular Signaling, Institute for Advanced Medical Research, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 1608582, Japan) ,  Tsukamoto Nobuo (Division of Cellular Signaling, Institute for Advanced Medical Research, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 1608582, Japan) ,  Hayashi Yuichiro (Department of Pathology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 1608582, Japan) ,  Kaseda Kaoru (Division of General Thoracic Surgery, Department of Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 1608582, Japan) ,  Kamiyama Ikuo (Division of General Thoracic Surgery, Department of Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 1608582, Japan) ,  Ohtsuka Takashi (Division of General Thoracic Surgery, Department of Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 1608582, Japan) ,  Tomizawa Kenji (Division of Thoracic Surgery, Department of Surgery, Kinki University Faculty of Medicine, 377-2, Ohnohigashi, Osaka-Sayama, Osaka 5898511, Japan) ,  Shimoji Masaki (Division of Thoracic Surgery, Department of Surgery, Kinki University Faculty of Medicine, 377-2, Ohnohigashi, Osaka-Sayama, Osaka 5898511, Japan) ,  Mitsudomi Tetsuya (Division of Thoracic Surgery, Department of Surgery, Kinki University Faculty of Medicine, 377-2, Ohnohigashi, Osaka-Sayama, Osaka 5898511, Japan) ,  Asamura Hisao (Division of General Thoracic Surgery, Department of Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 1608582, Japan) ,  Kawakami Yutaka (Division of Cellular Signaling, Institute for Advanced Medical Research, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 1608582, Japan)
Material： European Journal of Cancer  (Eur J Cancer)
Volume： 86  Page： 15-27  Publication year： 2017 
JST Material Number： A0802C  ISSN： 0959-8049  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： We have previously demonstrate...

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Thesaurus term： *patient ,  immunosuppression ,  gene expression ,  immersional wetting ,  *Adenocarcinoma ,  interferon gamma ,  tumor invasion ,  immunohistochemistry ,  non-small cell lung cancer ,  regulatory T cell ,  macrophage ,  immune cell ,  *microenvironment ,  *Adenocarcinoma lung ,  reaction ,  immune response ,  suppression and control ,  molecular genetic phenomenon
Semi thesaurus term： 非喫煙者 , 【Automatic Indexing@JST】

Author keywords (5)： Non-small cell lung cancer ,  Adenocarcinoma ,  Smoking history ,  Tumour microenvironment ,  Immunosuppression

JST classification (2)： Tumors(=neoplasms)of respiratory system  (GI04000G) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Terms in the title (6)： 肺腺癌 ,  非喫煙 ,  患者 ,  腫瘍微小環境 ,  予後不良 ,  免疫