Art

J-GLOBAL ID：201702247643749177   Reference number：17A0776968

Tissue toxicokinetics of perfluoro compounds with single and chronic low doses in male rats

雄ラットにおける単回および長期間低用量のペルフルオロ化合物の組織トキシコキネティクス

Author (10)： Iwabuchi Katsumi (Iwate Institute of Environmental Health Sciences) ,  Senzaki Norimasa (Iwate Institute of Environmental Health Sciences) ,  Mazawa Daichi (Faculty of Agriculture, Iwate University) ,  Sato Itaru (Faculty of Agriculture, Iwate University) ,  Hara Michihiro (Faculty of Agriculture, Iwate University) ,  Ueda Fukiko (School of Veterinary Medicine, Faculty of Veterinary Science, Nippon Veterinary and Life Science University) ,  Liu Wei (Key Laboratory of Industrial Ecology and Environmental Engineering (MOE), School of Environmental Science and Technology, Dalian University of Technology Dalian) ,  Tsuda Shuji (Iwate Institute of Environmental Health Sciences) ,  Tsuda Shuji (Faculty of Agriculture, Iwate University) ,  Tsuda Shuji (School of Veterinary Medicine, Faculty of Veterinary Science, Nippon Veterinary and Life Science University)
Material： Journal of Toxicological Sciences  (J Toxicol Sci)
Volume： 42  Issue： 3  Page： 301-317(J-STAGE)  Publication year： 2017 
JST Material Number： Z0265B  ISSN： 0388-1350  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： drug distribution ,...
Semi thesaurus term： *toxicokinetics

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Author keywords (4)： Perfluoro compounds ,  Perfluorohexanoic acid ,  Tissue specific distribution ,  Human tissue accumulation

JST classification (2)： Toxicity of organic compounds  (GZ02030Y) ,  Basic biopharmacy  (GY01021U)

Substance index (4)： Perfluorooctanesulfonic acid ,  Perfluorooctanoic acid ,  Heptadecafluorononanoic acid ,  Perfluorohexanoic acid

Reference (33)：

• Ahrens, L., Norström, K., Viktor, T., Cousins, AP. and Josefsson, S. (2015): Stockholm Arlanda Airport as a source of per- and polyfluoroalkyl substances to water, sediment and fish. Chemosphere, 129, 33-38.
• Andersen, M.E., Clewell, H.J.3rd., Tan, Y.M., Butenhoff, J.L. and Olsen, G.W. (2006): Pharmacokinetic modeling of saturable, renal resorption of perfluoroalkylacids in monkeys--probing the determinants of long plasma half-lives. Toxicology, 227, 156-164.
• Bischel, H.N., Macmanus-Spencer, L.A. and Luthy, R.G. (2010): Noncovalent interactions of long-chain perfluoroalkyl acids with serum albumin. Environ. Sci. Technol., 44, 5263-5269.
• Davies, B. and Morris, T. (1993): Physiological Parameters in Laboratory Animals and Humans. Pharm. Res., 10, 1093-1095.
• De Solla, S.R., De Silva, A.O. and Letcher, R.J. (2012): Highly elevated levels of perfluorooctane sulfonate and other perfluorinated acids found in biota and surface water downstream of an international airport, Hamilton, Ontario, Canada. Environ. Int., 39, 19-26.

Terms in the title (5)： ラット ,  低用量 ,  ペルフルオロ化合物 ,  組織 ,  トキシコキネティクス