Art

J-GLOBAL ID：201702251757460249   Reference number：17A0556794

The combination of elbasvir and grazoprevir for the treatment of chronic HCV infection in Japanese patients: a randomized phase II/III study

日本人患者における慢性HCV感染治療のためのエルバスビルとグラゾプレビルの併用:ランダム化第二相/第三相試験

Author (19)： KUMADA Hiromitsu (Toranomon Hospital, Kanagawa, JPN) ,  SUZUKI Yoshiyuki (Toranomon Hospital, Kanagawa, JPN) ,  KARINO Yoshiyasu (Sapporo Kosei General Hospital, Sapporo, JPN) ,  CHAYAMA Kazuaki (Hiroshima Univ., Hiroshima, JPN) ,  KAWADA Norifumi (Osaka City Univ. Medical School, Osaka, JPN) ,  OKANOUE Takeshi (Saiseikai Suita Hospital, Osaka, JPN) ,  ITOH Yoshito (Kyoto Prefectural Univ. Medicine, Kyoto, JPN) ,  MOCHIDA Satoshi (Saitama Medical Univ., Saitama, JPN) ,  TOYODA Hidenori (Ogaki Municipal Hospital, Ogaki, JPN) ,  YOSHIJI Hitoshi (Nara Medical Univ., Nara, JPN) ,  TAKAKI Shintaro (Hiroshima Red Cross Hospital and Atomic-Bomb Survivors Hospital, Hiroshima, JPN) ,  YATSUZUKA Naoyoshi (MSD K.K., Tokyo, JPN) ,  YODOYA Etsuo (MSD K.K., Tokyo, JPN) ,  IWASA Takashi (MSD K.K., Tokyo, JPN) ,  FUJIMOTO Go (MSD K.K., Tokyo, JPN) ,  ROBERTSON Michael N. (Merck & Co. Inc., NJ, USA) ,  BLACK Stuart (Merck & Co. Inc., NJ, USA) ,  CARO Luzelena (Merck & Co. Inc., NJ, USA) ,  WAHL Janice (Merck & Co. Inc., NJ, USA)
Material： Journal of Gastroenterology  (J Gastroenterol)
Volume： 52  Issue： 4  Page： 520-533  Publication year： 2017 
JST Material Number： Z0748A  ISSN： 0944-1174  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： Japan ,...
Semi thesaurus term： type C cirrhosis ,...

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JST classification (4)： Treatment for infectious diseases,parasitic diseases.  (GD01030D) ,  Digestive system diseases  (GH03000W) ,  Drug therapy(=pharmacotherapy)for digestive system diseases  (GH05020G) ,  Clinical application of antiviral drugs  (GW17050Z)

Substance index (2)： Elbasvir ,  Grazoprevir

Reference (20)：

• Gower E, Estes C, Blach S, et al. Global epidemiology and genotype distribution of the hepatitis C virus infection. J Hepatol. 2014;61(Suppl 1):S45-57.
• Lavanchy D. Evolving epidemiology of hepatitis C virus. Clin Microbiol Infect. 2011;17(2):107-15.
• Chung H, Ueda T, Kudo M. Changing trends in hepatitis C infection over the past 50 years in Japan. Intervirology. 2010;53(1):39-43.
• Yoshizawa H. Hepatocellular carcinoma associated with hepatitis C virus infection in Japan: projection to other countries in the foreseeable future. Oncology. 2002;62(Suppl 1):8-17.
• Asahina Y, Izumi N, Hiromitsu K, et al. JSH guidelines for the management of hepatitis C virus infection: a 2016 update for genotype 1 and 2. Hepatol Res. 2016;46(2):129-65.

Terms in the title (11)： 日本人 ,  患者 ,  慢性 ,  HCV感染 ,  治療 ,  エルバスビル ,  グラゾプレビル ,  併用 ,  ランダム化 ,  第二相 ,  第三相試験