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J-GLOBAL ID：201702253363566138   Reference number：17A0053416

Nivolumab-induced hypophysitis in a patient with advanced malignant melanoma

進行性悪性黒色腫患者におけるニボルマブ誘発下垂体炎

Author (15)： Okano Yudai (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Satoh Tetsurou (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Horiguchi Kazuhiko (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Toyoda Minoru (Department of Otolaryngology-Head and Neck Surgery, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Osaki Aya (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Matsumoto Shunichi (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Tomaru Takuya (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Nakajima Yasuyo (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Ishii Sumiyasu (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Ozawa Atsushi (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Shibusawa Nobuyuki (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Shimada Takehiro (Department of Diagnostic, Interventional Radiology and Nuclear Medicine, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Higuchi Tetsuya (Department of Diagnostic, Interventional Radiology and Nuclear Medicine, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Chikamatsu Kazuaki (Department of Otolaryngology-Head and Neck Surgery, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Yamada Masanobu (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan)
Material： Endocrine Journal  (Endocr J)
Volume： 63  Issue： 10  Page： 905-912(J-STAGE)  Publication year： 2016 
JST Material Number： F0625A  ISSN： 0918-8959  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： *nivolumab ,...

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Author keywords (5)： Malignant melanoma ,  Nivolumab ,  Hypophysitis ,  Secondary adrenal insufficiency ,  Treatment

JST classification (4)： Endocrine diseases  (GL03000I) ,  Skin tumors(=neoplasms)  (GF04000X) ,  Drug therapy(=pharmacotherapy)for tumors  (GE03032C) ,  Clinical application of antitumor(=antineoplastic)drugs  (GW16020L)

Substance index (1)： Cortisol

Reference (25)：

• 1. Caturegli P, Newschaffer C, Olivi A, Pomper MG, Burger PC, et al. (2005) Autoimmune hypophysitis. Endocr Rev 26: 599-614.
• 2. Umehara H, Okazaki K, Masaki Y, Kawano M, Yamamoto M, et al. (2012) A novel clinical entity, IgG4-related disease (IgG4RD): general concept and details. Mod Rheumatol 22: 1-14.
• 3. Bando H, Iguchi G, Fukuoka H, Taniguchi M, Yamamoto M, et al. (2013) The prevalence of IgG4-related hypophysitis in 170 consecutive patients with hypopituitarism and/or central diabetes insipidus and review of the literature. Eur J Endocrinol 170: 161-172.
• 4. Imura H, Nakao K, Shimatsu A, Ogawa Y, Sando T, et al. (1993) Lymphocytic infundibuloneurophysitis as a cause of central diabetes insipidus. N Engl J Med 329: 683-689.
• 5. Nishimura H, Honjo T (2001) PD-1: an inhibitory immunoreceptor involved in peripheral tolerance. Trends Immunol 22: 265-268.

Terms in the title (5)： 悪性黒色腫 ,  患者 ,  ニボルマブ ,  誘発 ,  下垂体炎