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J-GLOBAL ID：201702255985164849   Reference number：17A0578910

Geminin is an indispensable inhibitor of Cdt1 in mouse embryonic stem cells

Gemininはマウス胚性幹細胞におけるCdt1の不可欠な阻害剤である

Author (6)： Hosogane Masaki (Department of Cell Proliferation, United Center for Advanced Research and Translational Medicine, Graduate School of Medicine, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan) ,  Bosu Lena (Department of Cell Proliferation, United Center for Advanced Research and Translational Medicine, Graduate School of Medicine, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan) ,  Fukumoto Emiko (Department of Cell Proliferation, United Center for Advanced Research and Translational Medicine, Graduate School of Medicine, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan) ,  Yamada Hidetoshi (Department of Cell Proliferation, United Center for Advanced Research and Translational Medicine, Graduate School of Medicine, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan) ,  Sato Soichiro (Department of Cell Proliferation, United Center for Advanced Research and Translational Medicine, Graduate School of Medicine, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan) ,  Nakayama Keiko (Department of Cell Proliferation, United Center for Advanced Research and Translational Medicine, Graduate School of Medicine, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan)
Material： Genes to Cells  (Genes Cells)
Volume： 22  Issue： 4  Page： 360-375  Publication year： Apr. 2017 
JST Material Number： W0935A  ISSN： 1356-9597  CODEN： GECEFL  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： *protein ,...
Semi thesaurus term： *Geminin ,...

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JST classification (2)： Biological function  (EB03040U) ,  Cell physiology in general  (EF02010S)

Reference (48)：

• Alver, R.C., Chadha, G.S. & Blow, J.J. (2014) The contribution of dormant origins to genome stability: from cell biology to human genetics. DNA Repair 19, 182-189.
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• Ballabeni, A., Park, I.H., Zhao, R., Wang, W., Lerou, P.H., Daley, G.Q. & Kirschner, M.W. (2011) Cell cycle adaptations of embryonic stem cells. Proc. Natl Acad. Sci. USA 108, 19252-19257.
• Benjamin, J .M. , Torke, S J., Demeler, B. & McGarry, T.J. (2004) Geminin has dimerization, Cdt1-binding, and destruction domains that are required for biological activity. J. Biol. Chem. 279, 45957-45968.
• Blow, J.J. & Hodgson, B. (2002) Replication licensing-defining the proliferative state? Trends Cell Biol. 12, 72-78.

Terms in the title (4)： Geminin ,  マウス胚性幹細胞 ,  Cdt1 ,  阻害剤