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J-GLOBAL ID：201702262153926574   Reference number：17A0642303

Overexpression of endogenous 1-deoxy-d-xylulose 5-phosphate synthase (DXS) in cyanobacterium Synechocystis sp. PCC6803 accelerates protein aggregation

シアノバクテリアSynechocystis sp.PCC6803における内在性1-デオキシ-D-キシルロース5-リン酸シンターゼ(DXS)の過剰発現はタンパク質凝集を促進する

Author (10)： Kudoh Kai (Department of Bioscience and Food Production Science, Interdisciplinary Graduate School of Science and Technology, Shinshu University, 8304 Minamiminowa, Nagano 399-4511, Japan) ,  Hotta Shingo (Faculty of Agriculture, Shinshu University, 8304 Minamiminowa, Nagano 399-4511, Japan) ,  Sekine Midori (Faculty of Agriculture, Shinshu University, 8304 Minamiminowa, Nagano 399-4511, Japan) ,  Fujii Rintaro (Faculty of Agriculture, Shinshu University, 8304 Minamiminowa, Nagano 399-4511, Japan) ,  Uchida Arisu (Faculty of Agriculture, Shinshu University, 8304 Minamiminowa, Nagano 399-4511, Japan) ,  Kubota Genma (Faculty of Agriculture, Shinshu University, 8304 Minamiminowa, Nagano 399-4511, Japan) ,  Kawano Yusuke (Innovation Medical Research Institute, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan) ,  Ihara Masaki (Faculty of Agriculture, Shinshu University, 8304 Minamiminowa, Nagano 399-4511, Japan) ,  Ihara Masaki (JST, PRESTO, 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan) ,  Ihara Masaki (Department of Interdisciplinary Genome Sciences and Cell Metabolism, Institute for Biomedical Sciences, Interdisciplinary Cluster for Cutting Edge Research, Shinshu University, 8304 Minamiminowa, Kamiina, Nagano 399-4598, Japan)
Material： Journal of Bioscience and Bioengineering
Volume： 123  Issue： 5  Page： 590-596  Publication year： May. 2017 
JST Material Number： G0535B  ISSN： 1389-1723  CODEN： JBBIF6  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： Synechocystis ,...

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Author keywords (5)： Key words 1-Deoxyxylulose 5-phosphate synthase ,  MEP pathway ,  Protein solubility ,  Isoprene ,  Metabolic engineering

JST classification (1)： Enzyme physiology  (EG03052C)

Reference (30)：

• Rohmer, M., Seemann, M., Horbach, S., Bringer-Meyer, S., and Sahm, H.: Glyceraldehyde 3-phosphate and pyruvate as precursors of isoprenic units in an alternative non-mevalonate pathway for terpenoid biosynthesis, J. Am. Chem. Soc., 118, 2564-2566 (1996).
• Harker, M. and Bramley, P.: Expression of prokaryotic 1-deoxy-D-xylulose-5-phosphatases in Escherichia coli increases carotenoid and ubiquinone biosynthesis, FEBS Lett., 448, 115-119 (1999).
• Eisenreich, W., Bacher, A., Arigoni, D., and Rohdich, F.: Biosynthesis of isoprenoids via the non-mevalonate pathway, Cell. Mol. Life Sci., 61, 1401-1426 (2004).
• Kesselmeier, J. and Staudt, M.: Biogenic volatile organic compounds (VOC): an overview on emission, physiology and ecology, J. Atmos. Chem., 33, 23-88 (1999).
• Lindberg, P., Park, S., and Melis, A.: Engineering a platform for photosynthetic isoprene production in cyanobacteria, using Synechocystis as the model organism, Metab. Eng., 12, 70-79 (2010).

Terms in the title (7)： シアノバクテリア ,  Synechocystis ,  1-デオキシ-D-キシルロース5-リン酸 ,  シンターゼ ,  過剰発現 ,  タンパク質凝集 ,  促進