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J-GLOBAL ID：201702274227571063   Reference number：17A1697913

Low glucose induces mitochondrial reactive oxygen species via fatty acid oxidation in bovine aortic endothelial cells

低グルコースはウシ大動脈内皮細胞において脂肪酸酸化を介してミトコンドリア活性酸素種を誘導する

Author (10)： Kajihara Nobuhiro (Department of Metabolic Medicine, Kumamoto University, Kumamoto, Japan) ,  Kukidome Daisuke (Department of Metabolic Medicine, Kumamoto University, Kumamoto, Japan) ,  Sada Kiminori (Department of Metabolic Medicine, Kumamoto University, Kumamoto, Japan) ,  Motoshima Hiroyuki (Department of Metabolic Medicine, Kumamoto University, Kumamoto, Japan) ,  Furukawa Noboru (Department of Metabolic Medicine, Kumamoto University, Kumamoto, Japan) ,  Furukawa Noboru (Center for Medical Education and Research, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Matsumura Takeshi (Department of Metabolic Medicine, Kumamoto University, Kumamoto, Japan) ,  Nishikawa Takeshi (Department of Metabolic Medicine, Kumamoto University, Kumamoto, Japan) ,  Nishikawa Takeshi (Department of Diabetes and Endocrinology, National Hospital Organization Kumamoto Medical Center, Kumamoto, Japan) ,  Araki Eiichi (Department of Metabolic Medicine, Kumamoto University, Kumamoto, Japan)
Material： Journal of Diabetes Investigation (Web)  (JDI (Web))
Volume： 8  Issue： 6  Page： 750-761  Publication year： 2017 
JST Material Number： U0507A  ISSN： 2040-1124  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： cattle ,...
Semi thesaurus term： *fatty acid oxidation ,...

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Author keywords (3)： Fatty acid oxidation ,  Low glucose ,  Mitochondrial reactive oxygen species

JST classification (2)： Metabolic diseases,nutritional diseases in general.  (GD05010J) ,  Basic medicine on cardiovascular system  (GJ01020K)

Reference (35)：

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• Ceriello A, Testa R, Genovese S. Clinical implications of oxidative stress and potential role of natural antioxidants in diabetic vascular complications. Nutr Metab Cardiovasc Dis 2016; 26: 285-292.
• Schalkwijk CG, Stehouwer CD. Vascular complications in diabetes mellitus: the role of endothelial dysfunction. Clin Sci (Lond) 2005; 109: 143-159.
• Sheetz MJ, King GL. Molecular understanding of hyperglycemia’s adverse effects for diabetic complications. JAMA 2002; 288: 2579-2588.
• The Diabetes Control and Complications Trial Research Group. The relationship of glycemic exposure (HbA1c) to the risk of development and progression of retinopathy in the diabetes control and complications trial. Diabetes 1995; 44: 968-983.

Terms in the title (7)： グルコース ,  ウシ ,  大動脈内皮細胞 ,  脂肪酸酸化 ,  ミトコンドリア ,  活性酸素種 ,  誘導