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J-GLOBAL ID：201702281498164573   Reference number：17A1433354

Calcineurin inhibitors exacerbate coronary arteritis via the MyD88 signalling pathway in a murine model of Kawasaki disease

カルシニューリン阻害剤は,川崎病のマウスモデルにおけるMyD88シグナル伝達経路を介して冠動脈炎を悪化させる【Powered by NICT】

Author (19)： Murata K. (Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan) ,  Motomura Y. (Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan) ,  Motomura Y. (Division of Molecular Immunology, Research Center for Infectious Diseases, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan) ,  Tanaka T. (Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan) ,  Kanno S. (Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan) ,  Yano T. (Department of Pharmacy, Kyushu University Hospital, Fukuoka, Japan) ,  Onimaru M. (Division of Pathophysiological and Experimental Pathology, Department of Pathology, Kyushu University, Fukuoka, Japan) ,  Shimoyama A. (Department of Chemistry, Graduate School of Science, Osaka University, Osaka, Japan) ,  Nishio H. (Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan) ,  Sakai Y. (Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan) ,  Oh-Hora M. (Division of Molecular Immunology, Research Center for Infectious Diseases, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan) ,  Hara H. (Department of Immunology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan) ,  Fukase K. (Department of Chemistry, Graduate School of Science, Osaka University, Osaka, Japan) ,  Takada H. (Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan) ,  Masuda S. (Department of Pharmacy, Kyushu University Hospital, Fukuoka, Japan) ,  Ohga S. (Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan) ,  Yamasaki S. (Division of Molecular Immunology, Research Center for Infectious Diseases, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan) ,  Hara T. (Division of Molecular Immunology, Research Center for Infectious Diseases, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan) ,  Hara T. (Fukuoka Children’s Hospital, Fukuoka, Japan)
Material： Clinical and Experimental Immunology  (Clin Exp Immunol)
Volume： 190  Issue： 1  Page： 54-67  Publication year： 2017 
JST Material Number： E0159B  ISSN： 0009-9104  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Calcineurin inhibitors (CNIs) ...

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Thesaurus term： inflammation ,  therapy ,  protein ,  monocyte ,  in vitro experiment ,  *Kawasaki disease ,  macrophage ,  human(primates) ,  gene ,  cytokine ,  caspase ,  *coronary artery
Semi thesaurus term： *冠状動脈炎 ,  *MyD88 ,  *マウスモデル , 【Automatic Indexing@JST】

Author keywords (5)： calcineurin inhibitors ,  coronary arteritis ,  Kawasaki disease ,  mouse model ,  MyD88

JST classification (3)： Diseases specific to children  (GC08020M) ,  Cardiovascular system diseases  (GJ03000C) ,  Basic medicine on cardiovascular system  (GJ01020K)

Terms in the title (7)： カルシニューリン阻害剤 ,  川崎病 ,  マウスモデル ,  MyD88 ,  シグナル伝達経路 ,  冠動脈炎 ,  悪化