Art

J-GLOBAL ID：201702283139738808   Reference number：17A0461992

The isoflavone fraction from soybean presents mRNA maturation inhibition activity

ダイズ由来イソフラボン画分はmRNA成熟抑制活性を示す

Author (12)： KURATA Masashi (Kyoto Univ., Kyoto, JPN) ,  KURATA Masashi (Nagoya City Univ., Nagoya, JPN) ,  MURATA Yuki (Kyoto Women’s Univ., Kyoto, JPN) ,  MOMMA Keiko (Kyoto Women’s Univ., Kyoto, JPN) ,  ALI MURSI Intisar Fouad (Kyoto Univ., Kyoto, JPN) ,  TAKAHASHI Masakazu (Fukui Prefectural Univ., Fukui, JPN) ,  MIYAMAE Yusaku (Kyoto Univ., Kyoto, JPN) ,  KAMBE Taiho (Kyoto Univ., Kyoto, JPN) ,  NAGAO Masaya (Kyoto Univ., Kyoto, JPN) ,  NARITA Hiroshi (Kyoto Women’s Univ., Kyoto, JPN) ,  SHIBUYA Yasuyuki (Nagoya City Univ., Nagoya, JPN) ,  MASUDA Seiji (Kyoto Univ., Kyoto, JPN)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 81  Issue： 3  Page： 551-554  Publication year： Mar. 2017 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 短報  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *Glycine max ,...

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JST classification (3)： Pulses  (FC03035U) ,  Gene expression  (EC02040Q) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Substance index (1)： Isoflavone

Reference (26)：

• Papasaikas P, Valcarcel J. The spliceosome: the ultimate RNA chaperone and sculptor. Trends Biochem Sci. 2016;41:33-45.
• Saldi T, Cortazar MA, Sheridan RM, et al. Coupling of RNA polymerase II transcription elongation with pre-mRNA splicing. J Mol Biol. 2016;428:2623-2635.
• Wickramasinghe VO, Laskey RA. Control of mammalian gene expression by selective mRNA export. Nat Rev Mol Cell Biol. 2015;16:431-442.
• Daguenet E, Dujardin G, Valcarcel J. The pathogenicity of splicing defects: mechanistic insights into pre-mRNA processing inform novel therapeutic approaches. EMBO Rep. 2015;16:1640-1655.
• Maguire SL, Leonidou A, Wai P, et al. SF3B1 mutations consti- tute a novel therapeutic target in breast cancer. J Pathol. 2015;235:571-580.

Terms in the title (6)： ダイズ ,  イソフラボン ,  画分 ,  mRNA ,  成熟 ,  活性