Art

J-GLOBAL ID：201702286895484980   Reference number：17A0870691

Comparison of Efficacy and Safety of Azilsartan and Olmesartan in Patients With Essential Hypertension A Randomized and Prospective Study (CANZONE Study)

本態性高血圧の患者におけるアジルサルタンとオルメサルタンの効果と安全性の比較 ランダム化と前向き研究(CANZONE研究)

Author (24)： Shiga Yuhei (Department of Cardiology, Fukuoka University School of Medicine) ,  Shiga Yuhei (Inoue Hospital) ,  Shiga Yuhei (Fujisawa Clinic) ,  Shiga Yuhei (Shirotani Hospital) ,  Shiga Yuhei (Division of Cardiology, Izumi General Medical Center) ,  Miura Shin-ichiro (Department of Cardiology, Fukuoka University School of Medicine) ,  Miura Shin-ichiro (Department of Molecular Cardiovascular Therapeutics, Fukuoka University School of Medicine) ,  Motozato Kota (Department of Cardiology, Fukuoka University School of Medicine) ,  Motozato Kota (Division of Cardiology, Izumi General Medical Center) ,  Norimatsu Kenji (Department of Cardiology, Fukuoka University School of Medicine) ,  Yano Masaya (Department of Cardiology, Fukuoka University School of Medicine) ,  Yano Masaya (Fujisawa Clinic) ,  Hitaka Yuka (Department of Cardiology, Fukuoka University School of Medicine) ,  Hitaka Yuka (Inoue Hospital) ,  Adachi Sen (Department of Cardiology, Fukuoka University School of Medicine) ,  Kuwano Takashi (Department of Cardiology, Fukuoka University School of Medicine) ,  Inoue Ken (Inoue Hospital) ,  Inoue Asao (Inoue Hospital) ,  Fujisawa Kazuaki (Fujisawa Clinic) ,  Shirotani Tetsuro (Shirotani Hospital) ,  Kusumoto Takaaki (Division of Cardiology, Izumi General Medical Center) ,  Ideishi Munehito (Department of Cardiology, Fukuoka University School of Medicine) ,  Saku Keijiro (Department of Cardiology, Fukuoka University School of Medicine) ,  Saku Keijiro (Inoue Hospital)
Material： International Heart Journal  (Int Heart J)
Volume： 58  Issue： 3  Page： 416-421(J-STAGE)  Publication year： 2017 
JST Material Number： Z0752A  ISSN： 1349-2365  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...

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Author keywords (3)： Blood pressure ,  Angiotensin II type 1 receptor blocker ,  Uric acid

JST classification (1)： Drug therapy(=pharmacotherapy)for cardiovascular system diseases  (GJ05020M)

Substance index (4)： Azilsartan ,  Olmesartan ,  Creatinine ,  Uric Acid

Reference (24)：

• 1. Imaizumi S, Miura S, Yahiro E, Uehara Y, Komuro I, Saku K. Class- and molecule-specific differential effects of angiotensin II type 1 receptor blockers. Curr Pharm Des 2013; 19: 3002-8. (Review)
• 2. Adachi Y, Sakakura K, Wada H, et al. Determinants of left ventricular systolic function improvement following coronary artery revascularization in heart failure patients with reduced ejection fraction (HFrEF). Int Heart J 2016; 57: 565-72.
• 3. Miura S, Karnik SS and Saku K. Review: angiotensin II type 1 receptor blockers: class effects versus molecular effects. J Renin Angiotensin Aldosterone Syst 2011; 12: 1-7. (Review)
• 4. Fujino M, Miura S, Kiya Y, et al. A small difference in the molecular structure of angiotensin II receptor blockers induces AT1 receptor-dependent and -independent beneficial effects. Hypertens Res 2010; 33: 1044-52.
• 5. Ikeda Y, Kumagai H, Motozawa Y, Suzuki J, Komuro I. Next generation ARBs. Going beyond modulation of the renin-angiotensin system. Int Heart J 2015; 56: 585-6.

Terms in the title (6)： 本態性高血圧 ,  患者 ,  アジルサルタン ,  オルメサルタン ,  安全性 ,  研究