Art

J-GLOBAL ID：201702287326506003   Reference number：17A1813353

A phase II, multicenter, single-arm study of tri-weekly low-dose nanoparticle albumin-bound paclitaxel chemotherapy for patients with metastatic or recurrent breast cancer

転移性または再発性乳癌患者に対し3週間ごとに行う低用量ナノ粒子アルブミン結合パクリタキセル化学療法の第II相,多施設,単一群試験

Author (17)： YAMAMOTO Shigeru (Yamaguchi Univ. Graduate School of Medicine, Yamaguchi, JPN) ,  MAEDA Noriko (Yamaguchi Univ. Graduate School of Medicine, Yamaguchi, JPN) ,  NAGASHIMA Yukiko (Shimonoseki Medical Center, Yamaguchi, JPN) ,  KUBO Hidefumi (Tokuyama Univ. Hospital, Yamaguchi, JPN) ,  SATO Yoko (Yamaguchi Univ. Graduate School of Medicine, Yamaguchi, JPN) ,  MATSUI Hiroto (Yamaguchi Univ. Graduate School of Medicine, Yamaguchi, JPN) ,  INOUE Yuka (Yamaguchi Univ. Graduate School of Medicine, Yamaguchi, JPN) ,  SHINDO Yoshitaro (Yamaguchi Univ. Graduate School of Medicine, Yamaguchi, JPN) ,  KANEKIYO Shinsuke (Yamaguchi Univ. Graduate School of Medicine, Yamaguchi, JPN) ,  SAKAMOTO Kazuhiko (Yamaguchi Univ. Graduate School of Medicine, Yamaguchi, JPN) ,  SUZUKI Nobuaki (Yamaguchi Univ. Graduate School of Medicine, Yamaguchi, JPN) ,  TAKEDA Shigeru (Yamaguchi Univ. Graduate School of Medicine, Yamaguchi, JPN) ,  UENO Tomio (Yamaguchi Univ. Graduate School of Medicine, Yamaguchi, JPN) ,  YOSHINO Shigefumi (Yamaguchi Univ. Hospital, Yamaguchi, JPN) ,  HAZAMA Shoichi (Yamaguchi Univ. School of Medicine, Yamaguchi, JPN) ,  OKA Masaaki (Yamaguchi Univ., Yamaguchi, JPN) ,  NAGANO Hiroaki (Yamaguchi Univ. Graduate School of Medicine, Yamaguchi, JPN)
Material： Breast Cancer
Volume： 24  Issue： 6  Page： 783-789  Publication year： Nov. 2017 
JST Material Number： L3971A  ISSN： 1340-6868  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： *breast tumor ,...
Semi thesaurus term： *nanoparticle albumin-bound paclitaxel ,...

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JST classification (1)： Drug therapy(=pharmacotherapy)for gynecologic and obstetrical diseases  (GS05020N)

Reference (22)：

• Center for Cancer Control and Information Services, National Cancer Center, Japan. http://ganjoho.jp/public/index.html. Accesed 14 April 2017.
• Schiff PB, Fant J, Horwitz SB. Promotion of microtubule assembly in vitro by taxol. Nature. 1979;277:665-7.
• Jordan MA, Wendell K, Gardiner S, et al. Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death. Cancer Res. 1996;56:816-25.
• Ibrahim NK, Desai N, Legha S, et al. Phase I and pharmacokinetic study of ABI-007, a Cremophor-free, protein-stabilized, nanoparticle formulation of paclitaxel. Clin Cancer Res. 2002;8:1038-44.
• Gradishar WJ. Albumin-bound paclitaxel: a next-generation taxane. Expert Opin Pharmacother. 2006;7:1041-53.

Terms in the title (10)： 転移性 ,  再発 ,  乳 ,  癌患者 ,  低用量 ,  ナノ粒子アルブミン結合パクリタキセル ,  化学療法 ,  第II相 ,  施設 ,  試験