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J-GLOBAL ID：201702297325090999   Reference number：17A1169144

Live imaging of extracellular signal-regulated kinase and protein kinase A activities during thrombus formation in mice expressing biosensors based on Forster resonance energy transfer

Forster共鳴エネルギー移動に基づくバイオセンサを発現するマウスにおける血栓形成中の細胞外シグナル調節キナーゼと蛋白質キナーゼA活性のライブイメージング【Powered by NICT】

Author (11)： Hiratsuka T. (Department of Pathology and Biology of Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Sano T. (Department of Pathology and Biology of Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Kato H. (Department of Hematology-Oncology, Osaka University Graduate School of Medicine, Osaka, Japan) ,  Komatsu N. (Laboratory of Bioimaging and Cell Signaling, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Imajo M. (Laboratory of Bioimaging and Cell Signaling, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Kamioka Y. (Department of Pathology and Biology of Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Sumiyama K. (Laboratory for Mouse Genetic Engineering, Quantitative Biology Center, RIKEN, Suita, Osaka, Japan) ,  Banno F. (Research Institute, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan) ,  Miyata T. (Research Institute, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan) ,  Matsuda M. (Department of Pathology and Biology of Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Matsuda M. (Laboratory of Bioimaging and Cell Signaling, Graduate School of Medicine, Kyoto University, Kyoto, Japan)
Material： Journal of Thrombosis and Haemostasis  (J Thromb Haemost)
Volume： 15  Issue： 7  Page： 1487-1499  Publication year： 2017 
JST Material Number： W1621A  ISSN： 1538-7933  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Essentials Spatiotemporal regu...

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Thesaurus term： transgenic mouse ,  intravenous administration ,  in vitro experiment ,  *ERK ,  Platelet Aggregation ,  *protein kinase A ,  confocal microscope ,  Arterioles ,  *biosensor ,  Fluorescence ,  visualization ,  thrombocyte ,  *Thrombosis ,  bioimaging ,  *Thromboembolism ,  adenine nucleotide ,  ribonucleotide ,  cyclic nucleotide

Author keywords (5)： blood platelets ,  cAMP-dependent protein kinases ,  extracellular signal-regulated MAPKs ,  fluorescence resonance energy transfer ,  microscopy fluorescence multiphoton

JST classification (2)： Cell physiology in general  (EF02010S) ,  Biological function  (EB03040U)

Substance index (1)： cAMP

Terms in the title (9)： 共鳴エネルギー移動 ,  バイオセンサ ,  発現 ,  マウス ,  血栓形成 ,  細胞外シグナル調節キナーゼ ,  蛋白質キナーゼA ,  活性 ,  ライブイメージング