Nakatake Yuhki

Affiliation and department：

Research field (4)： Molecular biology , Pharmaceuticals - health and biochemistry , Systems genomics , Medical biochemistry

Research keywords (5)： transcriptional regulation , network , transcriptional factor , cell differentiation , stem cell

Papers (26)：

Ishii T, Ishikawa M, Fujimori K, Maeda T, Kushima I, Arioka Y, Mori D, Nakatake Y, Yamagata B, Nio S, et al. In Vitro Modeling of the Bipolar Disorder and Schizophrenia Using Patient-Derived Induced Pluripotent Stem Cells with Copy Number Variations of PCDH15 and RELN. eNeuro. 2019. 6. 5. ENEURO.0403-18.2019
Hiratsuka K, Monkawa T, Akiyama T, Nakatake Y, Oda M, Goparaju SK, Kimura H, Chikazawa-Nohtomi N, Sato S, Ishiguro K, et al. Induction of human pluripotent stem cells into kidney tissues by synthetic mRNAs encoding transcription factors. Scientific reports. 2019. 9. 1. 913
Ida H, Akiyama T, Ishiguro K, Goparaju SK, Nakatake Y, Chikazawa-Nohtomi N, Sato S, Kimura H, Yokoyama Y, Nagino M, et al. Establishment of a rapid and footprint-free protocol for differentiation of human embryonic stem cells into pancreatic endocrine cells with synthetic mRNAs encoding transcription factors. Stem cell research & therapy. 2018. 9. 1. 277
Fumiko Kusunoki Nakamoto, Satoshi Okamoto, Jun Mitsui, Takefumi Sone, Mitsuru Ishikawa, Yorihiro Yamamoto, Yumi Kanegae, Yuhki Nakatake, Kent Imaizumi, Hiroyuki Ishiura, et al. The pathogenesis linked to coenzyme Q10 insufficiency in iPSC-derived neurons from patients with multiple-system atrophy. Scientific reports. 2018. 8. 1. 14215-14215
Misako Matsushita, Yuhki Nakatake, Itaru Arai, Keiji Ibata, Kazuhisa Kohda, Sravan K. Goparaju, Miyako Murakami, Milci Sakota, Nana Chikazawa-Nohtomi, Shigeru B. H. Ko, et al. Neural differentiation of human embryonic stem cells induced by the transgene-mediated overexpression of single transcription factors. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2017. 490. 2. 296-301

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MISC (34)：

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Books (5)：

転写因子を用いた多能性幹細胞から任意細胞への分化誘導法の開発
実験医学増刊 Vol.33 No.2 2015
転写因子を自在に誘導できるES細胞バンクの作製とその応用
実験医学増刊 Vol.30、No.10 2012
多能性を司る機能を持つ転写因子
実験医学増刊Vol.25, No.6 2008
ヒトES細胞の未分化維持機構にもとづく培養法の改善
分子細胞治療 Vol.6, No.3 2007
糖尿病の再生医学-膵β細胞再生の基礎と臨床-胚性幹細胞における自己複製能と多分化能
最新医学第61巻・7号 2006

Lectures and oral presentations (10)：

ヒトES 細胞における網羅的な転写因子誘導株の樹立とその発現解析
(特定非営利活動法人バイオ計測技術コンソーシアムJMAC第118回定例会 2019)
ヒトES細胞における網羅的な転写因子誘導
(第311回発生研セミナー/発生研ミニシンポジウム 2017)
網羅的な遺伝子強制発現系とトランスクリプトームデータの活用・応用
(第8回数理デザイン道場~アイディアソン・ハッカソン 2017)
Large-scaled transgene activation on human embryonic stem cells
(2016)
ヒトES細胞における転写因子誘導の網羅的解析
(第14回日本再生医療学会総会 2015)

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Education (3)：

2001 - 2005 Graduate School of The University of Tokyo Department of Medicine Faculty of Medicine
1999 - 2001 Graduate School of Kyoto University Department of Pharmacy Faculty of Pharmaceutical Sciences,
1995 - 1999 Kyoto University Department of Pharmacy Faculty of Pharmaceutical Sciences

Work history (5)：

2018/04 - 現在 School of Medicine, Keio University Department of Systems Medicine, Mitsunada Sakaguchi Laboratory, Lecturer
2012/03 - 2018/03 School of Medicine, Keio University Department of Systems Medicine Mitsunada Sakaguchi Laboratory tenure-track assistant professor
2010/04 - 2012/02 National Institute of Health National Institute on Aging Researcher
2008/04 - 2010/03 National Institute of Health National Institute on Aging JSPS Postdoctral Fellowship for Research Abroad
2005/04 - 2008/03 RIKEN Center for Developmental Biology Researcher

Awards (1)：

2013/11 - Japan Science and Technology poster award CREST Biodynamics the second area conference

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