Rchr
J-GLOBAL ID：201801002685940079   Update date: Dec. 21, 2023

Nakao Kanako

Nakao Kanako
Research field  (3)： Tumor biology ,  Cell biology ,  Molecular biology
Research keywords  (8)： VHH ,  membrane protein ,  CFTR ,  Cystic fibrosis ,  Carcinoembryonic antigen ,  tumor marker ,  post-translational modification ,  ABC transporter
Research theme for competitive and other funds  (4)：
  • 2017 - 2020 新規CFTR関連疾患群の概念確立と治療薬開発をめざした日本人型CFTRの特性解析
  • 2014 - 2017 癌胎児性抗原CEAの腫瘍マーカーとしての新たなる展開
  • 2012 - 2014 腫瘍マーカーCEAにおける臓器特異性の検証
  • 2007 - 2009 ポストゲノム時代の挑戦:ABCG2タンパク質の品質管理と小胞体ストレス
Papers (31)：
  • Ryo Yonehara, Shigefumi Kumachi, Kenji Kashiwagi, Kanako Wakabayashi-Nakao, Maiko Motohashi, Taihei Murakami, Teruhiko Yanagisawa, Hidenao Arai, Akikazu Murakami, Yukio Ueno, et al. A novel agonist with homobivalent single-domain antibodies that bind the FGF receptor 1 domain III functions as an FGF2 ligand. The Journal of biological chemistry. 2023. 299. 2. 102804-102804
  • Taihei Murakami, Shigefumi Kumachi, Yasuhiro Matsunaga, Miwa Sato, Kanako Wakabayashi-Nakao, Hidekazu Masaki, Ryo Yonehara, Maiko Motohashi, Naoto Nemoto, Masayuki Tsuchiya. Construction of a Humanized Artificial VHH Library Reproducing Structural Features of Camelid VHHs for Therapeutics. Antibodies (Basel, Switzerland). 2022. 11. 1
  • Hiroki Anzai, Takuya Terai, Kanako Wakabayashi-Nakao, Taro Noguchi, Shigefumi Kumachi, Masayuki Tsuchiya, Naoto Nemoto. Interleukin-17A Peptide Aptamers with an Unexpected Binding Moiety Selected by cDNA Display under Heterogenous Conditions. ACS medicinal chemistry letters. 2021. 12. 9. 1427-1434
  • Keiichi Ohshima, Keiichi Hatakeyama, Kaori Kanto, Tomomi Ide, Yuko Watanabe, Sachi Moromizato, Kanako Wakabayashi-Nakao, Naoki Sakura, Ken Yamaguchi, Tohru Mochizuki. Comparative proteomic analysis identifies exosomal Eps8 protein as a potential metastatic biomarker for pancreatic cancer. Oncology reports. 2019. 41. 2. 1019-1034
  • Ryo Ashida, Yukiyasu Okamura, Kanako Wakabayashi-Nakao, Takashi Mizuno, Shuichi Aoki, Katsuhiko Uesaka. The Impact of Preoperative Enteral Nutrition Enriched with Eicosapentaenoic Acid on Postoperative Hypercytokinemia after Pancreatoduodenectomy: The Results of a Double-Blinded Randomized Controlled Trial. Digestive surgery. 2019. 36. 4. 348-356
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MISC (4)：
  • 中尾 香菜子, 正木 秀和, 土屋 政幸. 炎症・免疫領域における次世代VHH医薬品の開発動向. 炎症と免疫 / 「炎症と免疫」編集委員会 編. 2023. 31. 6. 578-581
  • Sohma Hikaru, Kimishima Rio, Ishizuka Shuta, Nakao Kanako, Sohma Yoshiro. Molecular dynamics simulation study on structural instability of CFTR mutants in Japanese CF patients and effects of CFTR correctors on them. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022. 96. 1-B-P-011
  • Hatakeyama Keiichi, Ohshima Keiichi, Wakabayashi-Nakao Kanako, Terashima Masanori, Yamaguchi Ken, Mochizuki Tohru. Novel Proteomic Approach for Identification of Protein Isoform Derived from Cancer-related Splicing Variants. Abstracts for Annual Meeting of Japanese Proteomics Society. 2011. 2011. 182-182
  • 若林香菜子, 中川大, 足立達彦, 喜井勲, 工藤明, 小畠英理, 石川智久. ヒトABCG2タンパク質の翻訳後修飾-Cys603を介した二量体形成-. 日本分子生物学会年会講演要旨集. 2005. 28th
Patents (7)：
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Professional career (1)：
  • 博士(工学) (東京工業大学)
Association Membership(s) (3)：
THE PHYSIOLOGICAL SOCIETY OF JAPAN ,  THE JAPANESE CANCER ASSOCIATION ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
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