Jianjun Xu

シイウジャンジュン | Jianjun Xu

Affiliation and department：
Homepage URL (1)： http://www.kufm.kagoshima-u.ac.jp/~physiol2/

Research field (4)： Physiology , Biophysics , Molecular biology , Neuroscience - general

Research keywords (9)：イオンチャネルチャネル , カルシウムチャネル , パッチクランプ , 蛋白質の結合 , 蛋白質のリン酸化 , 蛋白質の酸化 , 蛋白質精製 , 循環生理学 , 生理学

Research theme for competitive and other funds (5)：

2020 - 2022 Molecular mechanism of the regulation of Cav1.2 channels by calmodulin
2019 - 2021 Molecular mechanism of self-regulation of Cav1.2 channel by channel cytoplasmic fragments
2015 - 2017 Study on the regulatory mechanisms of L-type Ca2+ channels
2009 - 2011 An interrelation among regulatory mechanisms of cardiac Ca2+channels
2007 - 2008 Molecular mechanisms underlying Ca2^<+>-dependent facilitation and inactivation of L-type Ca^<2+> channels

Papers (26)：

Kameyama Masaki, Minobe Etsuko, Shao Dongxue, Xu Jianjun, Gao Qinghua, Hao Liying. Regulation of Cardiac Cav1.2 Channels by Calmodulin. International Journal of Molecular Sciences. 2023. 24. 6409. 1-28
Jianjun Xu, Etsuko Minobe, Masaki Kameyama. Ca2+ Dyshomeostasis Links Risk Factors to Neurodegeneration in Parkinson’s Disease. Frontiers in Cellular Neuroscience. 2022. 16. 867385. 1-15
Wanying Jia, Junyan Liu, Zhiyi Yu, Xiaohong Zhang, Xiaoxue Xu, Yuting Wang, Qinghua Gao, Rui Feng, Yujun Wan, Jianjun Xu, Etsuko Minobe, Masaki Kameyama, Wuyang Wang, Feng Guo. Properties of Calmodulin Binding to Na V 1.2 IQ Motif and Its Autism-Associated Mutation R1902C. Neurochemical Research. 2021. 46. 3. 523-534
Qinghua Gao, Etsuko Minobe, Masaki Kameyama, Jianjun Xu. Purification of insoluble GST-fused and GST-cleaved Cav1.2 channel fragment by denaturation and renaturation. Protein Expression and Purification. 2019. 160. 7-10
Jianing Li, Zhiyi Yu, Jianjun Xu, Rui Feng, Qinghua Gao, Tomasz Boczek, Junyan Liu, Zhi Li, Qianhui Wang, Ming Lei, Jian Gong, Huiyuan Hu, Etsuko Minobe, Hong-Long Ji , Masaki Kameyama, Feng Guo. The Effect of Ca2+, Lobe-Specificity, and CaMKII on CaM Binding to Nav1.1. International Journal of Molecular Sciences. 2018. 19. 9

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MISC (11)：

高青華, 雷明, 雷明, 徐建軍, 蓑部悦子, 朱曜南, HAO麗英, 亀山正樹. Cav1.2型Ca²⁺チャネルC末端部におけるPKAリン酸化のチャネル活性調節機序. 日本生理学雑誌(Web). 2018. 80. 2
Masaki Kameyama, Etsuko Minobe, Jianjun Xu, Dongyun Han, Hadhimulya Asmara, Asako Kameyama, Rui Feng, Shuyan Liu, Liying Hao. Regulation of L-type (Cav1.2) Ca2+ channels by calmodulin and ATP. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 45P-45P
Xu Jianjun, Etsuko Minobe, Yang Lei, Yu Lifeng, Asako Kameyama, Kazuto Yazawa, Masaki Kameyama. PKA modulates the Ca2+ channel activity induced by calmodulin in guinea-pig ventricular myocytes. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2013. 63. S192-S192
Feng Rui, Xu Jianjun, Etsuko Minobe, Asako Kameyama, Hao Li-Ying, Masaki Kameyama. ATP directly binds to cardiac Ca2+(Cav1.2)channels. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2013. 63. S195-S195
Aditya D. Joshi, Ruirui Ji, Jianjun Xu, Cheng Long, Susan L. Hamilton. Role of Oxidative Stress, Autophagy and Apoptosis in the I4895T RyR1 Knockin Mice. BIOPHYSICAL JOURNAL. 2010. 98. 3. 512A-512A

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Education (1)：

Professional career (1)：

Work history (4)：

Association Membership(s) (3)：

日本生理学会 , アメリカ生物物理学会 , 中国生理学会

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