Rchr
J-GLOBAL ID:201801005581964242   Update date: Aug. 18, 2022

Ohtsuki Takashi

オオツキ タカシ | Ohtsuki Takashi
Research field  (1): Medical biochemistry
Research keywords  (11): MMP ,  tissue regeneration ,  マトリックス分解酵素 ,  Extracellular vesicles ,  microRNA ,  exosome ,  mechanical stress ,  matrix ,  ADAMTS ,  connective tissue ,  cartilage
Research theme for competitive and other funds  (3):
  • 2016 - 2018 microRNAとエクソソーム解析によるメカニカルストレスの関節軟骨への作用解明
  • 2013 - 2016 ヒアルロン酸の変形性関節炎アップストリーム治療薬としての新展開と関節保護作用
  • 2010 - 2013 ヒアルロン酸による関節破壊抑制のメカニズム解析
Papers (19):
Patents (2):
  • 澱粉糊化食品の食味低下の抑制方法
  • イクラの製造方法
Lectures and oral presentations  (78):
  • Isolation and characterization of extracellular microvesicles in osteoarthritis
    (The 41st Annual Meeting of the molecular Biology Society of Japan 2018)
  • Mechanical stress attenuated inflammatory cytokines induced matrix degradative enzymes expression in chondrocyte by inhibition of NF-kB translocation
    (American Society for Matrix Biology Biennial Meeting 2018 2018)
  • Purification and characterization of exosome from chondrocyte conditioned medium and analysis of exosome up-taking mechanism in chondrocyte
    (Brainstorming 2018 2018)
  • Analysis of cartilage matrix degradation and regeneration mechanism
    (Brainstorming 2018 2018)
  • Isolation and characterization of matrix degradative microRNA
    (10th Annual Meeting of the Japan CCN family study group 2018)
more...
Education (3):
  • 2000 - 2006 Okayama university GRADUATE SCHOOL OF NATURAL SCIENCE AND TECHNOLOGY Molecular Biological Life Science
  • 1991 - 1993 Hiroshima university Graduate school of Science Biological Science
  • 1987 - 1991 Hiroshima university Faculty of Science Biological Science
Professional career (1):
  • 理学博士 (岡山大学)
Work history (5):
  • 2016/02 - 現在 Okayama university Non parmanent researcher
  • 2017/08 - 2017/09 Cleveland Clinic Lerner Research Institute Department of Biomedical Engineering Research Scholar
  • 2015/06 - 2016/01 Okayama university assistant professor
  • 2014/09 - 2015/05 Okayama university Non parmanent researcher
  • 1993/04 - 2004/06 Hayashibara Biochemical Laboratories Fujisaki Institute
Awards (1):
  • 2015/06 - International Society for Hyaluronan Sciences Travel Awards HYALURONAN TREATMENT REDUCED MATRIX DEGRADATION BOTH IN VITRO AND IN VIVO RAT OSTEOARTHRITIS MODEL.
Association Membership(s) (4):
American Society for Matrix Biology ,  Japanese Society for Matrix Biology and Medicine ,  Japanese Society of Cartilage Metabolism ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
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