Rchr
J-GLOBAL ID:201801006169242379
Update date: Sep. 16, 2024
Eiki Yamashita
ヤマシタ エイキ | Eiki Yamashita
Affiliation and department:
Research field (1):
Structural biochemistry
Research theme for competitive and other funds (18):
- 2022 - 2026 緑膿菌の多剤耐性化機構の解明に向けた薬剤排出タンパク質複合体の構造基盤
- 2021 - 2024 多剤排出タンパク質複合体の阻害剤開発に向けた基質との網羅的な構造活性相関解析
- 2019 - 2022 Structure basis for multidrug resistance efflux pump spanning both membranes in Pseudomonas aeruginosa
- 2013 - 2016 Structural basis for multidrug tripartite efflux pump through both the inner and outer membranes in Pseudomonas aeruginosa.
- 2010 - 2016 Structural basis of cell-signaling complexes mediating signal perception, transduction and responses.
- 2010 - 2015 Structural basis for nuclear transport mechanism by the nuclear transport receptor and improvement of a synchrotron beamline.
- 2009 - 2014 X-ray crystallographic studies of intr- and inter-cellular transport
- 2010 - 2012 Elucidation of nuclear export machinery of tRNA by crystal structural analysis of exportin/tRNA complex
- 2004 - 2009 High resolution X-ray crystal structural analysis of biological macromolecular assemblies
- 2006 - 2008 Crystal structural analysis of connexin-26 gap junction channel to elucidate functional mechanism of gap junction
- 2006 - 2007 チトクロム酸化酵素結晶の高精度高分解能X線回折強度データ収集システムの開発
- 2002 - 2005 Complete Structural Determination of Rice dwarf virus
- 2002 - 2003 原子レベルの立体構造に基づくチトクロム酸化酵素の動作機構の解明
- 2001 - 2002 膜蛋白質複合体チトクロム酸化酵素分子内のリン脂質の構造と機能研究
- 2001 - 2002 体外超分子複合体結晶のための低分解能の高精度X線回折強度データ測定法の開発
- 1999 - 2002 生体超分子複合体の構造解析への多波長異常分散法の利用
- 1998 - 1999 Structure Analysis of bovine heart cytochrome bc1 Complex at 2.3A resolution
- 1998 - 1999 精密X線結晶構造解析によるチトクロム酸化酵素の翻訳後修飾構造の決定
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Papers (140):
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Atsushi Mukaiyama, Yoshihiko Furuike, Kumiko Ito-Miwa, Yasuhiro Onoue, Kota Horiuchi, Eiki Yamashita, Shuji Akiyama. Evolutionary Origins of Self-sustained Kai Protein Circadian Oscillators. 2024
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Yukina Mori, Eiki Yamashita, Atsushi Nakagawa, Tomoki Matsuzawa, Minoru Inagaki, Yoshifumi Aiba, Syu Tanaka, Syunya Hatori, Maeda Ayami, Shigeki Takeda. Determination of the three-dimensional structure of bacteriophage Mu(-) tail fiber and its characterization. Virology. 2024. 593. 110017-110017
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Yoshihiko Furuike, Eiki Yamashita, Shuji Akiyama. Structure-function relationship of KaiC around dawn. Biophysics and Physicobiology. 2024. 21. 1. n/a-n/a
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Atsuhiro Shimada, Jumpei Baba, Shuhei Nagao, Kyoko Shinzawa-Itoh, Eiki Yamashita, Kazumasa Muramoto, Tomitake Tsukihara, Shinya Yoshikawa. Crystallographic cyanide-probing for cytochrome c oxidase reveals structural bases suggesting that a putative proton transfer H-pathway pumps protons. The Journal of biological chemistry. 2023. 105277-105277
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Takaaki Kato, Ui Okada, Li-Wei Hung, Eiki Yamashita, Heung-Bok Kim, Chang-Yub Kim, Thomas C. Terwilliger, Herbert P. Schweizer, Satoshi Murakami. Crystal structures of multidrug efflux transporters from Burkholderia pseudomallei suggest details of transport mechanism. Proceedings of the National Academy of Sciences. 2023. 120. 29
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MISC (330):
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慈幸千真理, 中野敦樹, 三角裕子, 山下栄樹, 栗栖源嗣, 森本幸生, 月原冨武, 横山謙, GERLE Christoph. Development of a novel purification method and structural analysis of mammalian FoF1ATP synthase. KURNS-EKR (Web). 2024. 19
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堤研太, 比嘉悠貴, 中川敦史, 山下栄樹. ヘテロ三量体型多剤排出トランスポーターMuxBCの構造解析. 日本結晶学会年会講演要旨集. 2023. 2023
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上田雄士, 米原涼, 池田悦子, 中川敦史, 山下栄樹. 多剤排出トランスポーターMexBの中性付近の結晶構造解析. 日本結晶学会年会講演要旨集. 2023. 2023
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松田真, 山下栄樹, 梶原健太郎, 赤松香奈子, 杉本楓, 岡田雅人, 中川敦史. がん進展に関わるCDCP1の結晶構造解析. 日本結晶学会年会講演要旨集. 2023. 2023
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森有希奈, 山下栄樹, 中川敦史, 武田茂樹. Three-dimensional structure of bacteriophage Mu tail fiber and structural comparison with the other tail fiber of Mu phage. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
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Patents (1):
Education (4):
- 1995 - 1997 Osaka University Graduate School of Science
- 1994 - 1995 The University of Tokushima Graduate School of Engineering
- 1992 - 1994 The University of Tokushima Graduate School of Engineering
- 1988 - 1992 The University of Tokushima Faculty of Engineering Department of Biological Science and Technology
Professional career (1):
Work history (4):
- 2017/01 - 現在 Osaka University Institute for Protein Research
- 2007/04 - 2017/12 Osaka University
- 1997/07 - 2007/03 Osaka University Institute for Protein Research
- 1997/04 - 1997/06 Japan Society for the Promotion of Science
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